SYNTHESIS OF CHROMENO[2,3-<i>b</i>]CHROMENES FROM 2-DIMETHYLAMINOPHENOLS AND MALONONITRILE

Authors

  • В. А. Осянин Samara State Technical University
  • Д. В. Осипов Samara State Technical University
  • Д. Д. Борисов Samara State Technical University
  • Ю. Н. Климочкин Samara State Technical University

DOI:

https://doi.org/10.1007/615

Keywords:

2-amino-4H-chromene-3-carbonitriles, chromeno[2, 3-b]chromenes, Mannich base, o-quinone methides, cascade reactions, [4 2] cycloadditions

Abstract

5a-Amino-5aH,11H-chromeno[2,3-b]chromene-11a(12H)-carbonitriles were synthesized from malononitrile and o-quinone methides, generated in situ by the thermolysis of phenolic Mannich bases in the presence of 1,8-diazabicyclo[5.4.0]undec-7-ene. It was also shown that this heterocyclic system can be obtained from 2-amino-4H-chromene-3-carbonitriles and the aforementioned o-quinone methides.

Authors: V. A. Osyanin, D. V. Osipov, D. D. Borisov, and Yu. N. Klimochkin

English Translation in Chemistry of Heterocyclic Compounds, 2013, 49 (5), pp 683-688

http://link.springer.com/article/10.1007/s10593-013-1298-x

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Published

2013-05-16

Issue

No. 5 (2013)

Section

Original Papers