QUINAZOLINES. 4*. ACYLATION OF QUINAZOLINE- 2,4-DIONES WITH AROMATIC ACIDS CHLORIDES IN THE PRESENCE OF FERRIC CHLORIDE HEXAHYDRATE

Authors

  • Р. Ш. Курязов S. Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences, Republic of Uzbekistan, Tashkent 100170
  • Ю. Р. Тахиров S. Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences, Republic of Uzbekistan, Tashkent 100170
  • Д. А. Душамов S. Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences, Republic of Uzbekistan, Tashkent 100170
  • Н. С. Мухамедов S. Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences, Republic of Uzbekistan, Tashkent 100170
  • К. К. Тургунов S. Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences, Republic of Uzbekistan, Tashkent 100170
  • Х. М. Шахидоятов S. Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences, Republic of Uzbekistan, Tashkent 100170
  • Б. Ташходжаев S. Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences, Republic of Uzbekistan, Tashkent 100170

DOI:

https://doi.org/10.1007/6153

Keywords:

6-aroylquinazoline-2, 4-diones, quinazoline-2, aromatic acid chlorides, acylation, X-ray structural analysis

Abstract

The interaction of quinazoline-2,4-diones with aromatic acids chlorides in nitrobenzene has been investigated in the presence of FeCl3∙6H2O. Optimum conditions for the acylation reaction have been developed, the used 4-substituted benzoyl chlorides have been put in order of relative activity, depending on the degree of their electrophilicity.

How to Cite
Kuryazov, R. Sh.; Takhirov, Yu. R.; Dushamov, D. A.; Mukhamedov, N. S.; Turgunov, K. K.; Shakhidoyatov, Kh. M.; Tashkhodjaev, B. Chem. Heterocycl. Compd. 2011, 46, 1380. [Khim. Geterotsikl. Soedin. 2010, 1702.]

For this article in the English edition see DOI 10.1007/s10593-011-0675-6

Published

2021-02-12

Issue

Section

Original Papers