QUINAZOLINES. 2. UNSYMMETRIC 1,3-DIALKYL-6-CHLOROSULFONYLQUINAZOLINE-2,4-DIONES IN NUCLEOPHILIC SUBSTITUTION REACTIONS

Authors

  • Р. Ш. Курязов Acad. S. Yu. Yunusov Institute of Vegetable the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Tashkent 100170
  • Н. С. Мухамедов Acad. S. Yu. Yunusov Institute of Vegetable the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Tashkent 100170
  • Х. М. Шахидоятов Acad. S. Yu. Yunusov Institute of Vegetable the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Tashkent 100170

DOI:

https://doi.org/10.1007/6237

Keywords:

amides of 2, 4-dioxoquinazoline-6-sulfonic acid, 2, 4-dioxoquinaxoline-6-sulfonic acids, unsymmetrical 1, 3-dialkylquinazoline-2, 4-diones, 6-chlorosulfonylquinazoline-2, nucleophilic and electrophilic substitution

Abstract

The corresponding 6-chlorosulfonylquinazoline-2,4-diones were synthesized by the reactions of 1‑methylquinazoline-2,4-dione and its 3-alkyl-substituted derivatives with chlorosulfonic acid. Treatment of the products with nucleophilic agents (water or ammonia, aliphatic and cyclic amines) gave 2,4-dioxoquinazolin-6-sulfonic acids or their amides.

How to Cite
Kuryazov, R. Sh.; Mukhamedov,  N. S.; Shakhidoyatov, Kh. M.  Chem. Heterocycl. Compd. 2009, 45, 1508. [Khim. Geterotsikl. Soedin. 2010, 1870.]

For this article in the English edition see DOI 10.1007/s10593-010-0458-5

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Published

2021-03-26

Issue

No. 12 (2009)

Section

Original Papers