SYNTHESIS AND ISOMERISM OF 2-(3,5-DIARYL-1H-PYRAZOL-4-YL)-1H-BENZIMIDAZOLES

Authors

  • И. Б. Дзвинчук Institute of Organic Chemistry, National Academy of Sciences of Ukraine, Kiev 02094
  • А. В. Туров Kiev Taras Shevchenko National University, Kiev 01033
  • М. О. Лозинский Institute of Organic Chemistry, National Academy of Sciences of Ukraine, Kiev 02094

DOI:

https://doi.org/10.1007/6442

Keywords:

aroylhydrazines, aroylhydrazones, benzimidazoles, pyrazoles, tautomerism

Abstract

2-(3,5-Diaryl-1H-pyrazol-4-yl)-1H-benzimidazoles  have been obtained by the cyclocondensation of 2-phenacyl-1H-benzimidazoles with 4-nitro- and 4-methoxybenzoylhydrazines. The reaction mechanism and the isomerism of the obtained products are discussed. According to the data of  1H NMR spectroscopy the stabilized isomer is that in which the electron-withdrawing aryl substituent is located in position 3 and the electron-donating substituent in position 5 of the pyrazole ring.

How to Cite
Dzvinchuk, I. B.; Turov, A. V.; Lozinskii, M. O. Chem. Heterocycl. Compd. 2009, 45, 1325.[Khim. Geterotsikl. Soedin. 2009, 1651.]

For this article in the English edition see DOI 10.1007/s10593-010-0429-x

 

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Published

2021-10-06

Issue

No. 11 (2009)

Section

Original Papers