SYNTHESIS OF SOME NEW HETARYLPYRANOPYRIDAZINES, CINNOLINES, AND HETARYLPYRIDAZINE DERIVATIVES

Authors

  • M. Abdel-Megid Department of Chemistry, Faculty of Education, Ain Shams University, Roxy, Cairo 11711
  • Y. Gabr Department of Chemistry, Faculty of Education, Ain Shams University, Roxy, Cairo 11711
  • M. A. A. Awas Department of Chemistry, Faculty of Education, Ain Shams University, Roxy, Cairo 11711
  • N. M. Abdel-Fatah Department of Chemistry, Faculty of Education, Ain Shams University, Roxy, Cairo 11711

DOI:

https://doi.org/10.1007/6448

Keywords:

cinnolines, pyranopyridazines, ring−chain tautomerism

Abstract

4-Acetyl-5,6-diphenylpyridazin-3(2H)-one was condensed with 6-chloro-3-formylchromone under different reaction conditions to yield  the  enone or pyranopyridazine. Both  compounds  were used in the synthesis of some new hetarylpyranopyridazines. Pyranodipyridazine was obtained  via a sequence of reactions of 4-acetyl-5,6-diphenylpyridazin-3(2H)-one with diethyl carbonate, acetic  anhydride, and  4-bromo-
benzenediazonium  chloride.  The reactions of pyridazinylbutane-1,3-dione with conc. H2SO4, POCl3, hydrazines, hydroxylamine hydrochloride, cyanoacetamide, thiourea, and thiosemicarbazone were also studied.

How to Cite
Abdel-Megid,M.; Gabr, Y.; Awas, M. A. A.; Abdel-Fatah, N. M.  Chem. Heterocycl. Compd. 2009, 45, 1354. [Khim. Geterotsikl. Soedin. 2009, 1684.]

For this article in the English edition see DOI 10.1007/s10593-010-0433-1

Published

2021-10-07

Issue

Section

Original Papers