SYNTHESIS OF NOVEL γ-BUTYROLACTONE-BASED PHENAZINE COMPOUNDS <i>VIA</i> MICROWAVE-ASSISTED MULTICOMPONENT DOMINO REACTIONS

Authors

  • Ha-Thanh Nguyen Institute of Chemistry, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet St., Cau Giay, Hanoi Graduate University of Science and Technology, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet St., Cau Giay, Hanoi
  • Phuong Hoang Thi Institute of Chemistry, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet St., Cau Giay, Hanoi
  • Giang Le-Nhat-Thuy Institute of Chemistry, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet St., Cau Giay, Hanoi Graduate University of Science and Technology, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet St., Cau Giay, Hanoi
  • Quynh Giang Nguyen Thi Institute of Chemistry, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet St., Cau Giay, Hanoi Graduate University of Science and Technology, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet St., Cau Giay, Hanoi
  • Tuan Anh Nguyen Institute of Chemistry, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet St., Cau Giay, Hanoi
  • Tuyet Anh Dang Thi Institute of Chemistry, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet St., Cau Giay, Hanoi Graduate University of Science and Technology, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet St., Cau Giay, Hanoi
  • Tuyen Van Nguyen Institute of Chemistry, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet St., Cau Giay, Hanoi Graduate University of Science and Technology, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet St., Cau Giay, Hanoi

DOI:

https://doi.org/10.1007/6843

Keywords:

γ-butyrolactone, naphthoquinone, phenazine, microwave-assisted multicomponent reaction

Abstract

A series of new and significative γ-butyrolactone-based phenazines were synthesized through two-step one-pot five-component reactions of 2-hydroxy-1,4-naphthoquinone, a variety of aromatic aldehydes, benzene-1,2-diamine, tetronic acid, and ammonium acetate in glacial acetic acid. The synthesis proceeded via condensation, Michael addition, tautomerization sequence of steps. All the synthesized compounds were fully characterized by spectral data.

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Published

2022-12-20

Issue

Vol. 58 No. 12 (2022)

Section

Original Papers