4-HYDROXY-2-QUINOLONES. 145. <i>p</i>-TOLUENESULFONYLHYDRAZIDE AS A TOSYLATING AGENT

Authors

  • И. В. Украинец National Pharmaceutial University, Kharkiv 61002
  • А. А. Ткач National Pharmaceutial University, Kharkiv 61002
  • В. В. Кравцова National Pharmaceutial University, Kharkiv 61002
  • С. В. Шишкина STC Institute for Single Crystal, Ukraine National Academy of Sciences, Kharkiv 61001

DOI:

https://doi.org/10.1007/7089

Keywords:

4-chloro-2-oxo-1, 2-dihydroquinoline-3-carboxylate, p-toluenesulfonylhydrazide X-ray structural analysis, tosylation

Abstract

The reaction of ethyl 4-chloro-1-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylate with p-toluene-sulfonylhydrazide in anhydrous solvents in the presence of triethylamine results in the tosylation of position 4 of the quinolone. Features of the steric structure of the tosyl-substituted compound are discussed.

How to Cite
Ukrainets, I. V.; Tkach, A. A.; Kravtsova, V. V.; Shishkina, S. V.  Chem. Heterocycl. Compd. 2008, 44, 677. [Khim. Geterotsikl. Soedin. 2008, 847.]

For this article in the English edition see DOI 10.1007/s10593-008-0109-2


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Published

2022-09-29

Issue

No. 6 (2008)

Section

Original Papers