THE USE OF 3-AMINO-4,6-DIMETHYLPYRAZOLO[3,4-<i>b</i>]PYRIDINE IN THE SYNTHESIS OF NOVEL HETEROCYCLES OF PHARMACEUTICAL INTEREST

Authors

  • M. A. Metwally Department of Chemistry, Faculty of Science, University of Mansoura, P.O. Box 23, Mansoura
  • H. A. Etman Department of Chemistry, Faculty of Science, University of Mansoura, P.O. Box 23, Mansoura
  • H. E. Gafer Department of Chemistry, Faculty of Science, University of Mansoura, P.O. Box 23, Mansoura
  • A. M. Khalil Department of Chemistry, Faculty of Science, University of Mansoura, P.O. Box 23, Mansoura

DOI:

https://doi.org/10.1007/7095

Keywords:

pyrazolo[4, 3-e]pyrido[2', 3', 3, 4]pyrazolo[1, 5-a]pyrimidines, pyrido[2', substituted[3, 4-b]pyridines

Abstract

3-Amino-4,6-dimethylpyrazolo[3,4-b]pyridine was used for the preparation of some novel heterocycles of pharmaceutical interest. The starting material reacted with 2-cyano-
3,3-bis(methylthio)acrylate, chloroacetyl chloride, phenyl isothiocyanate, carbon disul-
fide, and aromatic aldehydes to give the novel heterocycles.  The structures of the hitherto unknown ring systems have been confirmed by analytical and spectral methods.

How to Cite
Metwally, M. A.; Etman, H. A.; Gafer, H. E.; Khalil, A. M.   Chem. Heterocycl. Compd. 2008, 44, 715. [Khim. Geterotsikl. Soedin. 2008, 891.]

For this article in the English edition see DOI 10.1007/s10593-008-0103-8

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Published

2022-09-30

Issue

No. 6 (2008)

Section

Original Papers