SYNTHESIS AND ALKYLATION OF N<sub>(3)</sub>-ARYL-N<sub>(5)</sub>-PHENYL-6-AMINO-4-ARYL(2-FURYL)-2-THIOXO-1,2,3,4-TETRAHYDROPYRIDINE-3,5-DICARBOXAMIDE

Authors

  • В. Д. Дяченко Lugansk Taras Shevchenko National Pedagogical University, Lugansk 91011
  • Д. А. Красников Lugansk Taras Shevchenko National Pedagogical University, Lugansk 91011
  • М. В. Хорик Lugansk Taras Shevchenko National Pedagogical University, Lugansk 91011

DOI:

https://doi.org/10.1007/7115

Keywords:

dihydropyridines, tetrahydropyridines, alkylation, heterocyclization, Michael reaction

Abstract

N(3)-Aryl-N(5)-phenyl-6-amino-4-aryl(2-furyl)-2-thioxo-1,2,3,4-tetrahydropyridine-3,5-dicarboxamides have been obtained by the interaction of N-phenyl-3-aryl(2-furyl)-2-cyanoacrylamides with 3-amino-3-thioxopropananilides under the conditions of the Michael reaction. N(3)-Aryl-N(5)-phenyl-2-alkylthio-6-amino-4-aryl(2-furyl)-3,4-dihydropyridine-3,5-dicarboxamides and N(3),N(5)-diphenyl-6-benzylthio-
4-(2-furyl)-2-oxo-1,2,3,4-tetrahydropyridine-3,5-dicarboxamides were synthesized by alkylation of the products.

How to Cite
Dyachenko, V. D.; Krasnikov, D. A.; Khorik, M. V.  Chem. Heterocycl. Compd. 2008, 44, 815. [Khim. Geterotsikl. Soedin. 2008, 1018.]

For this article in the English edition see DOI 10.1007/s10593-008-0114-5


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Published

2022-10-06

Issue

No. 7 (2008)

Section

Original Papers