INVESTIGATIONS IN 2,3'-BIQUINOLINE SERIES. 24. SYNTHESIS OF 3-HETARYLQUINOLINES AND THEIR 1,4-DIHYDRO DERIVATIVES UNDER CONDITIONS OF THE VILSMEIER REACTION

Authors

  • Т. П. Глущенко Stavropol State University, Stavropol 355009
  • В. И. Гончаров Stavropol State Medical Academy, Stavropol 355017
  • А. В. Аксенов Stavropol State University, Stavropol 355009

DOI:

https://doi.org/10.1007/7156

Keywords:

acid amides, 2, 3'-biquinolines, 1', 4'-dihydro-2, 3-pyrid-2-ylquinolines, 3-pyrazin-2-ylquinoline, Vilsmeier reaction, cyclization

Abstract

Methods have been developed for the synthesis of 2,3'-biquinolines, their 1',4'-dihydro derivatives, 3-pyrid-2-ylquinolines, and 3-pyrazin-2-ylquinoline  based on the interaction of hetarylethylenes and vinyl butyl ether with imidoyl chlorides and Vilsmeier complexes. Using the example of the synthesis of 3-hetarylquinolines and their dihydro derivatives the  synthetic possibilities of the Vilsmeier method were shown for creating various bonds in different quinoline nuclei of the bisheterocyclic system.

How to Cite
Glushenko, T. P.; Goncharov, V. I.; Aksenov, A. V.  Chem. Heterocycl. Compd. 2008, 44, 973. [Khim. Geterotsikl. Soedin. 2008, 1209.]

For this article in the English edition see DOI 10.1007/s10593-008-0138-x


Published

2022-10-24

Issue

Section

Original Papers