INVESTIGATIONS IN 2,3'-BIQUINOLINE SERIES. 24. SYNTHESIS OF 3-HETARYLQUINOLINES AND THEIR 1,4-DIHYDRO DERIVATIVES UNDER CONDITIONS OF THE VILSMEIER REACTION
DOI:
https://doi.org/10.1007/7156Keywords:
acid amides, 2, 3'-biquinolines, 1', 4'-dihydro-2, 3-pyrid-2-ylquinolines, 3-pyrazin-2-ylquinoline, Vilsmeier reaction, cyclizationAbstract
Methods have been developed for the synthesis of 2,3'-biquinolines, their 1',4'-dihydro derivatives, 3-pyrid-2-ylquinolines, and 3-pyrazin-2-ylquinoline based on the interaction of hetarylethylenes and vinyl butyl ether with imidoyl chlorides and Vilsmeier complexes. Using the example of the synthesis of 3-hetarylquinolines and their dihydro derivatives the synthetic possibilities of the Vilsmeier method were shown for creating various bonds in different quinoline nuclei of the bisheterocyclic system.How to Cite
Glushenko, T. P.; Goncharov, V. I.; Aksenov, A. V. Chem. Heterocycl. Compd. 2008, 44, 973. [Khim. Geterotsikl. Soedin. 2008, 1209.]
For this article in the English edition see DOI 10.1007/s10593-008-0138-x