SYNTHESIS OF UNNATURAL AMINO ACIDS CONTAINING THE 3,7-DIAZABICYCLO[3,3,1]NONANE UNIT
DOI:
https://doi.org/10.1007/7160Keywords:
bis(methoxycarbonylmethyl) sulfone, 3, 7-diazabicyclo[3, 1]nonan-9-ones, diethyl 3-oxo-glutarate, unnatural amino acids, 9-thia-3, 1]nonane 9, 9-dioxide, Mannich reactionAbstract
Unnatural amino acids containing the 3,7-diazabicyclo[3,3,1]nonane unit were synthesized in one step by the reaction of diethyl 3-oxoglutarate, bis(methoxycarbonylmethyl) sulfone, with formaldehyde and primary amino acids under conditions of the Mannich reaction.How to Cite
Latypova, D. R.; Vlasova, L. I.; Baibulatova, N. Z.; Lobov, A. N.; Spirikhin, L. V.; Dokichev, V. A. Chem. Heterocycl. Compd. 2008, 44, 996. [Khim. Geterotsikl. Soedin. 2008, 1236.]
For this article in the English edition see DOI 10.1007/s10593-008-0146-x