4-HYDROXY-2-QUINOLONES. 149. SYNTHESIS, CHEMICAL TRANSFORMATIONS, AND BIOLOGICAL PROPERTIES OF β-N-ACYLHYDRAZIDES OF 1-R-4-HYDROXY-2-OXO-1,2-DIHYDROQUINOLINE-4-CARBOXYLIC ACIDS

Abstract

Two methods of preparation have been proposed and the synthesis has been effected of a large series of β-N-acylhydrazides of 1-R-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxylic acids. The possibility of using various condensing agents for converting them into the corresponding 1,3,4-oxa-diazoloquinolines has been studied. Results are given of an investigation of the antitubercular activity of the synthesized compounds.

How to Cite
Ukrainets, I. V.; Tkach, A. A.; Yang, L. Y.  Chem. Heterocycl. Compd. 2008, 44, 1347. [Khim. Geterotsikl. Soedin. 2008, 1655.]

For this article in the English edition see DOI 10.1007/s10593-009-0198-6