SYNTHESIS AND REACTIVITY OF 3-AMINO-9-METHOXYMETHYL-7-METHYL-3,4-DIHYDROPYRIDO[3',2':4,5]THIENO[3,2-<i>d</i>PYRIMIDIN-4-ONES

Authors

  • Е. С. Костенко Kuban State Technological University, Krasnodar 350072
  • М. М. Липунов Kuban State Technological University, Krasnodar 350072
  • Е. А. Кайгородова Kuban State Agrarian University, Krasnodar 350044
  • Л. Д. Конюшкин N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow 119992

DOI:

https://doi.org/10.1007/7347

Keywords:

3-amino-3, 4-dihydropyrido[3', 2', 4, 5]thieno[3, 2-d]pyrimidin-4-ones, hydrazine hydrate, ethyl 3-aminothienopyridinecarboxylate, desulfurization, Raney nickel

Abstract

The reaction of acyl derivatives of ethyl 3-aminothieno[2,3-b]pyridine-2-carboxylate with hydrazine hydrate gives a series of tricyclic 3-amino-3,4-dihydropyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-ones containing aliphatic, aromatic, or  heteroaromatic fragments at C(2). The reactions of 3-amino-pyridothieno[3,2-d]pyrimidin-4-ones with aldehydes, formamide, 2,5-dimethoxytetrahydrofuran, acetic anhydride, and Raney nickel were studied.

How to Cite
Kostenko, E. S.; Lipunov, M. M.; Kaigorodova, E. A.; Konyushkin, L. D.  Chem. Heterocycl. Compd. 2007, 43, 1466. [Khim. Geterotsikl. Soedin. 2007, 1720.]

For this article in the English edition see DOI 10.1007/s10593-007-0226-3


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Published

2023-01-23

Issue

No. 11 (2007)

Section

Original Papers