A NEW APPROACH TO THE SYNTHESIS OF INDOLE- AND BENZOFURAN-CONTAINING TETRACYCLIC CONDENSED SYSTEMS

Authors

  • Т. Е. Хоштария Georgian Technical University, Tbilisi 380075
  • Л. Н. Курковская Georgian Technical University, Tbilisi 380075
  • М. М. Матнадзе Georgian Technical University, Tbilisi 380075
  • М. И. Сихарулидзе Georgian Technical University, Tbilisi 380075
  • В. О. Ананиашвили Georgian Technical University, Tbilisi 380075
  • Т. О. Джаши Georgian Technical University, Tbilisi 380075
  • К. Т. Бацикадзе Georgian Technical University, Tbilisi 380075

DOI:

https://doi.org/10.1007/7363

Keywords:

indole, pyrrole

Abstract

A new method is described for the synthesis of the 1H-benzo[b]furoindole heterocyclic systems from the corresponding isomeric amino acids with amino groups at positions 2 and 3. By  this method  it  is possible to obtain these tetracyclic systems not only in the form of one isomer but also to convert them from one to the other. From the  tetracyclic  systems with angular structure it is possible to obtain the corresponding linear isomers. On the other hand, from the isomer with the linear structure it is possible to change to the isomer with angular fusion of the pyrrole ring. The classical Fischer reaction served as model for such transformations.

How to Cite
Khoshtariya, T. E.; Kurkovskaya, L. N.; Matnadze, M. M.; Sikharulidze, M. I.; Ananiashvili, V. O.; Dzhashi, T. O.; Batsikadze, K. T.  Chem. Heterocycl. Compd. 2007, 43, 1239. [Khim. Geterotsikl. Soedin. 2007, 1463.]

For this article in the English edition see DOI 10.1007/s10593-007-0189-4

 

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Published

2023-01-24

Issue

No. 10 (2007)

Section

Original Papers