TRIFLUOROACETYLATION OF PYRROLO[1,2-<i.a</i>]PYRAZINES

Authors

  • В. И. Теренин M. V. Lomonosov Moscow State University, Chemistry Faculty, Moscow 119899
  • Е. В. Кабанова M. V. Lomonosov Moscow State University, Chemistry Faculty, Moscow 119899
  • Н. А. Целищева M. V. Lomonosov Moscow State University, Chemistry Faculty, Moscow 119899
  • А. С. Иванов M. V. Lomonosov Moscow State University, Chemistry Faculty, Moscow 119899
  • Н. В. Зык M. V. Lomonosov Moscow State University, Chemistry Faculty, Moscow 119899

DOI:

https://doi.org/10.1007/7424

Keywords:

pyrrolo[1, 2-a]pyrazine, trifluoroacetic anhydride, trifluoroacetylation

Abstract

A study was carried out on the reaction of pyrrolo[1,2-a]pyrazines containing an alkyl, aryl, or aralkyl substituent at C-1 with trifluoroacetic anhydride. Trifluoroacetylation products may be formed either by reaction in the pyrrole ring or at the aryl or aralkyl groups at C-1. Products of electrophilic substitution at C-6 are formed in the trifluoroacetylation of pyrrolo[1,2-a]pyrazines containing at C-1 a substituent bulkier than a methyl group but lacking substituents at C-6 (the α-position of the pyrrole ring).

How to Cite
Terenin, V. I.; Kabanova, E. V.; Tselishcheva, N. A.; Ivanov, A. S.; Zyk, N. V.  Chem. Heterocycl. Compd. 2007, 43, 1038. [Khim. Geterotsikl. Soedin. 2007, 1226.]

For this article in the English edition see DOI 10.1007/s10593-007-0162-2


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Published

2023-02-02

Issue

No. 8 (2007)

Section

Original Papers