4-HYDROXY-2-QUINOLONES. 121. SYNTHESIS AND BIOLOGICAL PROPERTIES OF 1-HYDROXY-3-OXO-5,6-DIHYDRO-3H-PYRROLO[3,2,1-<i>ij</i>]QUINOLINE-2-CARBOXYLIC ACID ALKYLAMIDES

Authors

  • И. В. Украинец National University of Pharmacy, Kharkiv 61002
  • Н. Л. Березнякова National University of Pharmacy, Kharkiv 61002
  • Е. В. Моспанова National University of Pharmacy, Kharkiv 61002

DOI:

https://doi.org/10.1007/7447

Keywords:

alkylamides, 4-hydroxy-2-oxoquinoline-3-carboxylic acids, diuretic activity, anti-inflammatory activity, X-ray structural analysis

Abstract

A  simple  method is proposed for preparing 1-hydroxy-3-oxo-5,6-dihydro-3H-pyrrolo[3,2,1-ij]-quinoline-2-carboxylic acid alkylamides. For the case of the secondary butylamide features of the steric structure of the synthesized compounds  is  discussed. The results of a study of their anti-inflammatory and diuretic activities are presented.

How to Cite
Ukrainets, I. V.; Bereznyakova, N. L.; Mospanova, E. V.  Chem. Heterocycl. Compd. 2007, 43, 856. [Khim. Geterotsikl. Soedin. 2007, 1015.]

For this article in the English edition see DOI 10.1007/s10593-007-0136-4


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Published

2023-02-13

Issue

No. 7 (2007)

Section

Original Papers