4-HYDROXY-2-QUINOLONES. 122. 1-HYDROXY-3-OXO-5,6-DIHYDRO-3H-PYRROLO[3,2,1-<i>ij</i>]QUINOLINE-2-CARBOXYLIC ACID HETARYLAMIDES AS POTENTIAL ANTITUBERCULAR AGENTS

Authors

  • И. В. Украинец National University of Pharmacy, Kharkiv 61002
  • Е. В. Моспанова National University of Pharmacy, Kharkiv 61002
  • Л. В. Сидоренко National University of Pharmacy, Kharkiv 61002

DOI:

https://doi.org/10.1007/7448

Keywords:

hetarylamides, 4-hydroxy-2-oxoquinoline-3-carboxylic acids, amidation, antitubercular activity

Abstract

An improved method is reported for the synthesis of a series of 1-hydroxy-3-oxo-5,6-dihydro-3H-pyrrolo[3,2,1-ij]quinoline-2-carboxylic acid hetarylamides. The antitubercular activity of all of the compounds prepared has been studied. The structure – biological activity dependence revealed is discussed.

How to Cite
Ukrainets, I. V.; Mospanova, E. V.; Sidorenko, L. V.  Chem. Heterocycl. Compd. 2007, 43, 863. [Khim. Geterotsikl. Soedin. 2007, 1023.]

For this article in the English edition see DOI 10.1007/s10593-007-0137-3

 

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Published

2023-02-13

Issue

No. 7 (2007)

Section

Original Papers