SYNTHESIS, CRYSTAL AND MOLECULAR STRUCTURE OF 2-(3-CHLOROPROPYL)-6-METHYL-4-PHENYLQUINAZOLINE 3-OXIDE

Abstract

The acylation of the syn isomer of the oxime of 2-amino-5-methylbenzophenone with 4-chlorobutyryl chloride  gives a mixture of the anti isomer of the 4-chlorobutyryloximine of 2-(4-chlorobutyryl)amino-5-methylbenzophenone and 2-(3-chloropropyl)-6-methyl-4-phenylquinazoline 3-oxide. The crystal  and molecular structure of this oxide was established by X-ray diffraction structural analysis. The molecule is planar. The electron impact  fragmentation of  2-(3-chloropropyl)-6-methyl-4-phenylquinazoline 3-oxide was discussed.

How to Cite
Kulikov, O. V.; Mazepa, A. V.  Chem. Heterocycl. Compd. 2007, 43, 879. [Khim. Geterotsikl. Soedin. 2007, 1043.]

For this article in the English edition see DOI 10.1007/s10593-007-0139-1