4-HYDROXY-2-QUINOLONES. 118. SYNTHESIS, STRUCTURE, AND CHEMICAL PROPERTIES OF 2-BROMOMETHYL-5-OXO-1,2-DIHYDRO-5H-OXAZOLO[3,2-<i>a</i>]QUINOLINE-4-CARBOXYLIC ACID AND ITS ETHYL ESTER

Authors

  • И. В. Украинец National University of Pharmacy, Kharkiv 61002
  • Л. В. Сидоренко National University of Pharmacy, Kharkiv 61002
  • О. В. Горохова National University of Pharmacy, Kharkiv 61002
  • С. В. Шишкина NTC Institute for Single Crystals, National Academy of Sciences Ukraine, Kharkiv 61001
  • А. В. Туров Taras Shevchenko Kiev National University, Kiev 01033

DOI:

https://doi.org/10.1007/7527

Keywords:

oxazolo[3, 2-a]quinoline-4-carboxylic acid, bromination, heterocyclization, hydrolysis, X-ray analysis

Abstract

Bromination of N-allyl-substituted  4-hydroxy-2-quinolinones with molecular bromine in acetic acid or carbon tetrachloride occurs with closing of a five membered oxazole ring to give 2-bromomethyl-5-oxo-1,2-dihydro-5H-oxazolo[3,2-a]quinoline.

How to Cite
Ukrainets, I. V.; Sidorenko, L. V.; Gorokhova, O. V.; Shishkina, S. V.; Turov, A. V.  Chem. Heterocycl. Compd. 2007, 43, 617. [Khim. Geterotsikl. Soedin. 2007, 736.]

For this article in the English edition see DOI 10.1007/s10593-007-0096-8

 

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Published

2023-03-21

Issue

No. 5 (2007)

Section

Original Papers