NEW OXAZOLE TO OXAZOLE RECYCLIZATION

Авторы

  • Oleh V. Shablykin V. P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry, National Academy of Sciences of Ukraine, 1 Akademika Kukharya St., Kyiv 02094, Ukraine
  • Danylo О. Merzhyievskyi V. P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry, National Academy of Sciences of Ukraine, 1 Akademika Kukharya St., Kyiv 02094, Ukraine
  • Volodymyr S. Brovarets Institute of Bioorganic Chemistry and Petrochemistry, National Academy of Sciences of Ukraine
  • Svitlana V. Shishkina State Scientific Institution ''Institute for Single Crystals'', National Academy of Sciences of Ukraine, 60 Nauky Ave., Kharkiv 61001, Ukraine

DOI:

https://doi.org/10.1007/7623

Ключевые слова:

5-aminooxazole-4-carbonitrile, 5-aminooxazole-4-carboxamide, oxazolo[5, 4-d]pyrimidin-7(6H)-one, trifluoroacetic acid, recyclization.

Аннотация

(4-Cyanooxazol-5-ylamino)acetates and (4-cyanooxazol-5-ylamino)acetamides after treatment with trifluoroacetic acid undergo recyclization to the mixture of corresponding 5-aminooxazoles, 5-trifluoroacetylaminooxazoles, and oxazolopyrimidinones. The structures have been confirmed for certain products which have been isolated in pure form.

Биография автора

Volodymyr S. Brovarets, Institute of Bioorganic Chemistry and Petrochemistry, National Academy of Sciences of Ukraine

Chemistry of bioactive nitrogen-containing heterocyclic bases Dr. Chem. Sci., Prof.

Загрузки

Опубликован

2023-08-09

Выпуск

Том 59 № 6/7 (2023): UKRAINIAN IMPACT ON HETEROCYCLIC CHEMISTRY AFTER THE THREE DECADES OF INDEPENDENCE

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