SYNTHESIS OF NEW 2-AMINO-5-HYDROXYMETHYL-2-THIAZOLINES

Authors

  • Т. П. Трофимова M. V. Lomonosov Moscow State University, Chemical Faculty, Moscow 119992
  • А. Н. Пушин Institute of Physiologically Active Compounds, Russian Academy of Sciences, Chernogolovka 142432
  • А. Н. Прошин Institute of Physiologically Active Compounds, Russian Academy of Sciences, Chernogolovka 142432
  • А. И. Сташ Karpov Institute of Physical Chemistry, Moscow 105064
  • А. А. Мандругин M. V. Lomonosov Moscow State University, Chemical Faculty, Moscow 119992
  • В. М. Федосеев M. V. Lomonosov Moscow State University, Chemical Faculty, Moscow 119992
  • С. Я. Проскуряков Medical Radiological Research Center, Russian Academy of Medical Sciences, Obninsk 249036, Moscow Region

DOI:

https://doi.org/10.1007/7651

Keywords:

2-amino-5-hydroxymethyl-2-thiazoline, , nitric oxide, hydrolysis, X-ray structural analysis, NMR

Abstract

A simple and convenient method is proposed for the synthesis of 2-amino-5-hydroxymethylthiazolines with various substituents in the amino group, which is based on hydrolysis of the corresponding 5-halomethyl derivatives of thiazoline in the presence of divalent lead oxide.

How to Cite
Trofimova, T. P.; Pushin, A. N.; Proshin, A. N.; Stash, A. I.; Mandrugin, A. A.; Fedoseev, V. M.; Proskuryakov, S. Ya.  Chem. Heterocycl. Compd. 2007, 43, 370. [Khim. Geterotsikl. Soedin. 2007, 456.]

For this article in the English edition see DOI 10.1007/s10593-007-0054-5


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Published

2023-03-31

Issue

No. 3 (2007)

Section

Original Papers