4-HYDROXY-2-QUINOLONES. 111. SIMPLE SYNTHESIS OF 1-SUBSTITUTED 4-METHYL-2-OXO-1,2-DIHYDROQUINOLINE-3-CARBOXYLIC ACIDS

Authors

  • И. В. Украинец National Pharmaceutical University, Kharkiv 61002
  • О. В. Горохова National Pharmaceutical University, Kharkiv 61002
  • Л. В. Сидоренко National Pharmaceutical University, Kharkiv 61002
  • Н. Л. Березнякова National Pharmaceutical University, Kharkiv 61002

DOI:

https://doi.org/10.1007/7701

Keywords:

1-R-4-methyl-2-oxo-1, 2-dihydroquinoline-3-carboxylic acid, 4-chloroquinolin-2-one, cyanoacetic ester, amidation, hydrolysis, decarboxylation, X-ray structural analysis

Abstract

A preparative method of obtaining 1-substituted 4-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylic acids is proposed. Features of their spatial structure have been studied.

How to Cite
Ukrainets, I. V.; Gorokhova, O. V.; Sidorenko, L. V.; Bereznyakova, N. L.  Chem. Heterocycl. Compd. 2007, 43, 58. [Khim. Geterotsikl. Soedin. 2007, 69.]

For this article in the English edition see DOI 10.1007/s10593-007-0008-y


Published

2023-04-06

Issue

Section

Original Papers