SYNTHESIS AND INVESTIGATION OF SOME 1,4-DISUBSTITUTED 2-PYRROLIDINONES

Authors

  • K. Brokaitė Kaunas University of Technology, Kaunas 50254
  • V. Mickevičius Kaunas University of Technology, Kaunas 50254
  • G. Mikulskienė Institute of Biochemistry, Vilnius 08662

DOI:

https://doi.org/10.1007/7812

Keywords:

1-aryl-4-hydrazinecarbonyl-2-pyrrolidinones, hydrazones, Z/E-isomers, pyrazoles, condensation, spectroscopy

Abstract

A series of condensation products of 1-aryl-4-hydrazinecarbonyl-2-pyrrolidinones with acetone, 2,4-pentanedione, aromatic aldehydes was obtained and identified by the combination of IR, mass and  1H,  13C NMR spectroscopy. The results of their structural studies by NMR spectroscopy are provided. It was ascertained  that the presence of NH group determines the existence of the mixtures of Z/E-isomers of compounds under study. The availability of Z-isomer as a sterically favourable one was also verified by the computer molecular modeling.

How to Cite
Brokaitė, K.; Mickevičius, V.; Mikulskienė, G.  Chem. Heterocycl. Compd. 2006, 42, 1158. [Khim. Geterotsikl. Soedin. 2006, 1336.]

For this article in the English edition see DOI 10.1007/s10593-006-0220-1

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Published

2023-05-18

Issue

No. 9 (2006)

Section

Original Papers