INTERACTION OF (1-PHENYLETHYL)INDOLE-2-CARBONITRILE WITH C-NUCLEOPHILES

Authors

  • Н. Е. Голанцов Chemical Faculty, M. V. Lomonosov Moscow State University, Moscow 119992
  • А. В. Карчава Chemical Faculty, M. V. Lomonosov Moscow State University, Moscow 119992
  • М. А. Юровская Chemical Faculty, M. V. Lomonosov Moscow State University, Moscow 119992

DOI:

https://doi.org/10.1007/7839

Keywords:

enamino esters, 2-propionylindole, 1-(1-phenylethyl)indole-2-carbonitrile, [1-(1-phenylethyl)-2-indolyl]-1-propanone, ethyl ester of Z-3-amino-3-[1-(1-phenylethyl)-2-indolyl]acrylic acid, Blaise reaction, interactions with C-nucleophiles, N-dibenzylation

Abstract

Methods  of obtaining ketones and enamino esters have  been developed on the basis of reactions of 1-(1-phenylethyl)indole-2-carbonitrile with  organomagnesium and organozinc compounds. Removal of a benzyl group from the indole nitrogen atom by the Grignard reagent has been discovered.

How to Cite
Golantsov, N. E.; Karchava, A. V.; Yurovskaya, M. A.  Chem. Heterocycl. Compd. 2006, 42, 1021. [Khim. Geterotsikl. Soedin. 2006, 1179.]

For this article in the English edition see DOI 10.1007/s10593-006-0198-8

 

Published

2023-05-26

Issue

Section

Original Papers