REACTION OF 2,3-DIOXOPYRROLO[2,1-<i>a</i>]ISOQUINOLINES WITH AROMATIC AND SECONDARY ALIPHATIC AMINES

Authors

  • Н. Н. Полыгалова Perm State Pharmaceutical Academy, Perm 614990
  • А. Г. Михайловский Perm State Pharmaceutical Academy, Perm 614990

DOI:

https://doi.org/10.1007/8195

Keywords:

aromatic and heteroaromatic amines, 5, 5-dialkyl-2, 3-dioxopyrrolo[2, 1-a]isoquinolines, 1, 2, 3, 4-tetrahydroisoquinoline enamino ketoamides, acid catalysis

Abstract

It has been found that 2,3-dioxopyrrolo[2,1-a]isoquinolines react with aromatic amines in glacial acetic acid and with heteroaromatic and secondary aliphatic amines in the absence of acid with opening of the pyrroledione ring to give 1,2,3,4-tetrahydroisoquinoline enamino ketoamides.

How to Cite
Polygalova, N. N.; Mikhailovskii, A. G.  Chem. Heterocycl. Compd. 2005, 41, 1173. [Khim. Geterotsikl. Soedin. 2005, 1378.]

For this article in the English edition, see DOI 10.1007/s10593-005-0298-x


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Published

2023-10-25

Issue

No. 9 (2005)

Section

Original Papers