RING-CHAIN TAUTOMERISM OF 1,2,3,4-TETRAHYDROQUINAZOLINES. THE PRODUCTS OF REACTION OF 1,3-DICARBONYL COMPOUNDS WITH 2-AMINOMETHYLANILINE

Abstract

The reaction of 2-aminomethylaniline with 1,3-dicarbonyl compounds gives a series of 1,2,3,4-tetrahydroquinazoline derivatives. A ring-chain tautomeric equilibrium of the type enamine-1,2,3,4-tetrahydroquinazoline is observed in solutions of these compounds and its position depends of the structure of the starting dicarbonyl component and the solvent polarity.

How to Cite
Zelenin, K. N.; Potapov, A. A.; Alekseyev, V. V.; Lagoda, I. V. Chem. Heterocycl. Compd. 2004, 40, 903. [Khim. Geterotsikl. Soedin. 2004, 1052.]

For this article in the English edition, see DOI https://doi.org/10.1023/B:COHC.0000044573.19543.09