REACTIONS OF 2-AMINO-4-METHYL-6-(2-PYRIDYL)- AND 2-AMINO-4-METHYL-6-PHENYL-7,8-DIHYDROINDAZOLO[4,5-<i>d</i>]THIAZOLES WITH ALDEHYDES
Keywords:
2-amino-4-methyl-6-(2-pyridyl)- and 2-amino-4-methyl-6-phenyl-7,8-dihydroindazolo[4,5-d]thiazoles, aromatic aldehydes, 2-formyl-1,3-cyclanediones, Schiff basesAbstract
The reaction of 2-amino-4-methyl-6-(2-pyridyl)-7,8-dihydroindazolo[4,5-d]thiazole, obtained by treating 3-methyl-4-oxo-1-(2-pyridyl)-4,5,6,7-tetrahydroindazole with pyridinium bromide perbromide and then with thiourea, and 2-amino-4-methyl-6-phenyl-7,8-dihydroindazolo[4,5-d]thiazole with 4-bromo-, 4-fluoro-, 4-dimethylamino-, 4-methoxy-, 3,4-dimethoxy-, and 3,4-methylenedioxy-benzaldehydes, furfural, pyridinecarbaldehyde, and thiophenecarbaldehyde gave the corresponding Schiff bases. The products of the condensation of these aminothiazoles with cinnamaldehyde, 1-(2-pyridyl)- and 4-chloro-1-(2,4-difluorophenyl)-5-formyl-3-methyl-6,7-dihydroindazoles, 2-formyl-dimedone, and 2-formyl-1,3-indanedione were also obtained.
How to Cite
Strakova, I.; Petrova, M.; Strakovs, A. Chem. Heterocycl. Compd. 2004, 40, 938. [Khim. Geterotsikl. Soedin. 2004, 1089.]
For this article in the English edition, see DOI 10.1023/B:COHC.0000044579.61466.7b
