APPLICATION OF THE RECYCLIZATION PRODUCTS OF 5-ALKYL(ARYL)AMINO-2-(3-PHTHALIMIDOPROPYL)-1,3-OXAZOLE-4-CARBONITRILES TO THE SYNTHESIS OF CONDENSED TRICYCLIC NITROGENOUS STRUCTURES
DOI:
https://doi.org/10.1007/860Keywords:
N-alkyl(aryl)-3-amino-5H, 6H, 7H-pyrrolo[1, 2-a]imidazole-2-carboxamides, 3-alkyl-2-mercapto-1, 2, 3, 6, 7, 8-hexahydro-4H-pyrrolo[2', 1', 3]imidazo[4, 5-d][1, 2]diazaphosphinine-4-thione 2-sulfides, 3 alkyl(aryl)-3H, 4H, 7H, 8H-pyrrolo[2, 1-h]purin-4-ones, 3-aryl-3H, 8H-pyrrolo-[2, 1 h]purine-4-thiones, recyclizationAbstract
N-Alkyl(aryl)-3-amino-5H,6H,7H-pyrrolo[1,2-a]imidazole-2-carboxamides were obtained by the interaction of 5-alkyl(aryl)amino-2-(3-phthalimidopropyl)-1,3-oxazole-4-carbonitriles with hydrazine hydrate and have been used for the synthesis of substituted 3H,4H,6H,7H,8H-pyrrolo[2,1-h]purin-4‑ones, their thione analogs, and also 1,2,3,6,7,8-hexahydro-4H-pyrrolo[2',1':2,3]imidazo[4,5-d]-[1,3,2]diazaphosphinine derivatives.
Authors: S. A. Chumachenko, O. V. Shablykin, and V. S. Brovarets
English Translation in Chemistry of Heterocyclic Compounds, 2013, 48 (12), pp 1832-1838
