The synthesis and antimicrobial activity of 6-aryl-2-spiro-substituted 5-trichloroacetyl-4<i>H</i>-1,3-dioxin-4-ones

Authors

  • Natalya Yu. Lisovenko Пермский государственный национальный исследовательский университет
  • Svetlana S. Kharitonova
  • Svetlana Yu. Balandina

Keywords:

acetyl ketenes, 4,5-disubstituted furan-2,3-diones, substituted 1,3-dioxin-4-ones, antimicrobial activity, regiospecificity, thermolysis

Abstract

Thermolysis of 5-aryl-4-trichloroacetylfuran-2,3-diones in the presence of cyclic ketones yielded 6-aryl-2-spiro-substituted 5trichloroacetyl-4H-1,3-dioxin-4-ones. The obtained compounds were screened for antimicrobial activity.

 

Author Biographies

Natalya Yu. Lisovenko, Пермский государственный национальный исследовательский университет

Perm State University,
15 Bukireva St., Perm 614990, Russia

Svetlana S. Kharitonova

Perm State University,
15 Bukireva St., Perm 614990, Russia

Svetlana Yu. Balandina

Perm State University,
15 Bukireva St., Perm 614990, Russia

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Published

2024-09-25

Issue

Vol. 60 No. 7/8 (2024)

Section

Original Papers