METHOD OF OBTAINING 6-ETHOXYCARBONYLMETHYLSULFINYL-2,3-DIHYDROXY-1,2,3,4-TETRAHYDROPYRIDINE

Authors

  • Л. Краснова Latvian Institute of Organic Synthesis
  • А. Краузе Latvian Institute of Organic Synthesis
  • С. Беляков Latvian Institute of Organic Synthesis
  • Г. Дубурс Latvian Institute of Organic Synthesis

DOI:

https://doi.org/10.1007/905

Keywords:

6-alkylsulfanyl-1, 4-dihydropyridine, 6-alkylsulfinyl-2, 3-dihydroxy-1, 2, 3, 4-tetrahydropyridine, 1, 4 dihydropyridine, oxone, m-chloroperbenzoic acid

Abstract

Oxidation of the sulfur atom in methyl 4-(2-chlorophenyl)-5-cyano-6-ethoxycarbonylmethylsulfanyl-2‑methyl-1,4-dihydropyridine-3-carboxylate with m-chloroperbenzoic acid in dichloromethane gave methyl 4-(2-chlorophenyl)-5-cyano-6-ethoxycarbonylmethylsulfinyl-2,3-dihydroxy-2-methyl-1,2,3,4-tetra-hydropyridine-3-carboxylate. The structure of the compound obtained was identified by 1H NMR spectroscopy and by X-ray structural analysis.

Authors: L. Krasnova, A. Krauze, S. Belyakov, and G. Duburs

English Translation in Chemistry of Heterocyclic Compounds, 2013, 48 (10), pp 1482-1486

http://link.springer.com/article/10.1007/s10593-013-1161-0

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Published

2013-08-28

Issue

No. 10 (2012)

Section

Original Papers