SYNTHESIS AND PROPERTIES OF DERIVATIVES OF THE NEW HETEROCYCLIC SYSTEM BENZ[4,5]IMIDAZO[1,2-<i>c</i>]PYRIDO-[3',2';4,5]THIENO[2,3-<i>e</i>]PYRIMIDINE

Authors

  • E. Ю. Камбулов Kuban State Technological University, Krasnodar 350072
  • B. K. Bасилин Kuban State Technological University, Krasnodar 350072
  • E. А. Кайгородова Kuban State Technological University, Krasnodar 350072
  • Л. Д. Конюшкин Kuban State Technological University, Krasnodar 350072
  • Г. Д. Крапивин Kuban State Technological University, Krasnodar 350072

Keywords:

3-amino-2-(benzimidazolyl)thieno[2,3-b]pyridines, 2-benzimidazolylmethylthio-3-cyanopyridines, benz[4,5]imidazo[1,2-c]pyrido[3',2';4,5]thieno[2,3-e]pyrimidines, 2-chloromethylbenzimidazole, 3-cyanopyridin-2(1H)-thiones

Abstract

Derivatives of a new heterocyclic system – benz[4,5]imidazo[1,2-c]pyrido[3',2';4,5]thieno[2,3-e]-pyrimidine have been obtained by successive reactions in three stages – alkylation of 3-cyanopyridine-2(1H)-thiones with 2-chloromethylbenzylimidazole to give 2-benzimidazolylmethylthio-3-cyanopyridines, closing the thiophene ring in the latter to form 3-amino-2-(benzimidazolyl-2)thieno[2,3-b]pyridines, and cyclization of the pyrimidine ring by acylation with carboxylic acid anhydrides or chlorides.

How to Cite
Kambulov, E. Yu.; Vasilin, V. K.; Kaigorodova, E. A.; Konyushkin, L. D.; Krapivin, G. D. Chem. Heterocycl. Compd. 2003, 39, 255. [Khim. Geterotsikl. Soedin. 2003, 287.]

For this article in the English edition, see DOI https://doi.org/10.1023/A:1023736928729

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Published

2003-02-25

Issue

No. 2 (2003)

Section

Original Papers