PROGRESS IN THE SYNTHESIS OF 3-FLUOROCHROMONES

Authors

  • Yelyzaveta Y. Rybina Taras Shevchenko National University of Kyiv
  • Viktoriia S. Moskvina Taras Shevchenko National University of Kyiv, V. P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry

Abstract

This microreview focuses exclusively on the synthetic methodologies for 3-fluorochromones, highlighting their unique pharmacophoric properties that arise from the combination of the chromone core with a fluorine atom. Although 3-fluorochromones have been studied extensively, their presence in the literature is still relatively limited. This review offers a detailed exploration of the existing research, following the progression of synthetic methods from the earliest strategies to the most recent innovations in the field.

Author Biographies

Yelyzaveta Y. Rybina, Taras Shevchenko National University of Kyiv

Taras Shevchenko National University of Kyiv,
64/13 Volodymyrska St., Kyiv 01033, Ukraine

Viktoriia S. Moskvina, Taras Shevchenko National University of Kyiv, V. P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry

Taras Shevchenko National University of Kyiv,
64/13 Volodymyrska St., Kyiv 01033, Ukraine

 

V. P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry,
National Academy of Sciences of Ukraine,
1 Akademika Kukharia St., Kyiv 02094, Ukraine

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Published

2024-12-13

Issue

Vol. 60 No. 9/10 (2024)

Section

Heterocycles in Focus