A REACTION OF AROYL(HETEROAROYL)PYRUVIC ACID ESTERS WITH 3,3-DIAMINOACRYLONITRILES: A NEW METHOD FOR THE SYNTHESIS OF PYRROLES WITH CONJUGATED EXOCYCLIC DOUBLE BONDS

Authors

  • Roman V. Kosonogov Perm State National Research University, 15 Bukireva St., Perm 614990
  • Yuliya G. Stepanyan Perm Institute (branch) of the Russian University of Economics named after G. V. Plekhanov, 57 Gagarin Blvd., Perm 614070
  • Tetyana V. Beryozkina Ural Federal University, 19 Mira St., Yekaterinburg 620002
  • Vladimir G. Ilkin Ural Federal University, 19 Mira St., Yekaterinburg 620002
  • Pavel S. Silaichev Perm State National Research University, 15 Bukireva St., Perm 614990
  • Vasiliy A. Bakulev Ural Federal University, 19 Mira St., Yekaterinburg 620002

Keywords:

3,3-diaminoacrylonitriles, methyl pyruvates, pyrroles, pyrrolones, C,N-binucleophilic reagents, cyclization, exocyclic bonds

Abstract

Pyrroles incorporating conjugated exocyclic C=C and C=O bonds were obtained in the reaction of 3,3-diaminoacrylonitriles with aroyl(heteroaroyl)pyruvic acid esters. A simple and efficient method for the synthesis of pyrroles was developed based on this reaction, which makes it possible to vary the substituents in positions 1 and 5 of the pyrrole ring and in the 2-oxoethylidene fragment.

Author Biography

Vasiliy A. Bakulev, Ural Federal University, 19 Mira St., Yekaterinburg 620002

The chief of the technologyfor Organic Synthesis Department

Downloads

Additional Files

Published

2024-12-13

Issue

Vol. 60 No. 9/10 (2024)

Section

Original Papers