FIRST EXAMPLE OF THE SYNTHESIS OF DI(FLUOROALKYL)-SUBSTITUTED PYRIMIDINES

Authors

  • О. Г. Кузуева Institute of Organic Synthesis, Urals Branch, Russian Academy of Sciences, Ekaterinburg 620219
  • Я. B. Бypгарт Institute of Organic Synthesis, Urals Branch, Russian Academy of Sciences, Ekaterinburg 620219
  • B. И. Caлоутин Institute of Organic Synthesis, Urals Branch, Russian Academy of Sciences, Ekaterinburg 620219
  • O. Н. Чупахин Institute of Organic Synthesis, Urals Branch, Russian Academy of Sciences, Ekaterinburg 620219

Keywords:

pyrimidines with fluoroalkyl substituents

Abstract

4,5-Bis(hydroxy)-4-trifluoromethyl-6-(fluoroalkyl)hexahydropyrimidin-2-ones (thiones) have been obtained for the first time by the reaction of ureas (thioureas) with di(fluoroalkyl)-substituted 1,3‑diketones and tetraols, the dehydration of which gave 2-hydroxy(mercapto)-4-trifluoromethyl-6-(fluoroalkyl)pyrimidines.

How to Cite
Kuzueva, O. G.; Burgart, Ya. V.; Saloutin, V. I.; Chupakhin, O. N. Chem. Heterocycl. Compd. 2001, 37, 1130. [Khim. Geterotsikl. Soedin. 2001, 1232.]

For this article in the English edition, see DOI https://doi.org/10.1023/A:1013235901570

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Published

2001-09-25

Issue

No. 9 (2001)

Section

Original Papers