SYNTHESIS OF 5-PHENYL-7-TRIFLUOROMETHYL-2,3-DIHYDROIMIDAZO[1,2-a]PYRIDINES

Authors

  • Е. Сулоева Riga Technical University, LV-1048 Riga
  • М. Юре Riga Technical University, LV-1048 Riga
  • Э. Гудриниеце Riga Technical University, LV-1048 Riga
  • С. Беляков Latvian Institute of Organic Synthesis, Riga LV-1006
  • М. Петрова Riga Technical University, LV-1048 Riga
  • И. Калните Riga Technical University, LV-1048 Riga

Keywords:

2,3-dihydroimidazo[1,2-a]pyridines, 2,3,4-trihydropyrido[1,2-a]pyrimidines, X-ray structural analysis

Abstract

Syntheses are reported for a series of 2-alkylamino-6-phenyl-4-trifluoromethylpyridines. The reaction of 3-cyano-2-(hydroxyalkylamino)-6-phenyl-4-trifluoromethylpyridines with thionyl chloride gave the corresponding 2-(chloroalkylamino)pyridines, 8-cyano-5-phenyl-7-trifluoromethyl-2,3-dihydro-imidazo[1,2-a]pyridines, and 9-cyano-6-phenyl-8-trifluoromethyl-2,3,4-trihydropyrido[1,2-a]-pyrimidines. X-ray diffraction structural analysis was used to study 8-cyano-5-phenyl-7-trifluoromethyl-2,3-dihydroimidazo[1,2-a]pyridine.

How to Cite
Suloeva, E.; Yure, M.; Gudriniece, E.; Belyakov, S.; Petrova, M.; Kalnite, I. Chem. Heterocycl. Compd. 2001, 37, 329. [Khim. Geterotsikl. Soedin. 2001, 358.]

For this article in the English edition, see DOI https://doi.org/10.1023/A:1017511217288

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Published

2001-03-25

Issue

No. 3 (2001)

Section

Original Papers