Synthesis of pyrazolo[1,5-<i>a</i>]pyrimidines by the reaction of β-dicarbonyl compounds with 3,5-diamino-4-nitropyrazole

Authors

  • В. А. Макаров M. V. Lomonosov Moscow State University, 119899 Moscow
  • В. А. Тафеенко Center for Pharmacological Chemistry, All-Russian Pharmaceutical Chemistry Institute, 119815 Moscow
  • В. Г. Граник Center for Pharmacological Chemistry, All-Russian Pharmaceutical Chemistry Institute, 119815 Moscow

Abstract

The reaction of 3,5-diamino-4-nitropyrazole with asymmetrical β-dicarbonyl compounds gave polysubstituted pyrazolo[1,5-a]pyrimidines, which are used in reactions with both nucleophilic and electrophilic reagents. The structure of the compounds obtained was demonstrated by X-ray diffraction structural analysis.

How to Cite
Makarov, V. A.; Tafeenko, V. A.; Granik, V. G. Chem. Heterocycl. Compd. 1998, 34, 1423. [Khim. Geterotsikl. Soedin. 1998, 1676.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF02317814

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Published

1998-12-25

Issue

No. 12 (1998)

Section

Original Papers