SYNTHESIS AND HUMAN LEUKOCYTE ELASTASE INHIBITORY ACTIVITY OF NOVEL 2-SPIRO(2',2'-DIPHENYLCYCLOPROPANE) CEPHALOSPORIN SULFONES

Authors

  • Andhe V. Narender Reddy SynPhar Laboratories Inc., #2, 4290-91А Street, Edmonton, Alberta T6E 5V2
  • Charles Y. Fiakpui SynPhar Laboratories Inc., #2, 4290-91А Street, Edmonton, Alberta T6E 5V2
  • David P. Czajkowski SynPhar Laboratories Inc., #2, 4290-91А Street, Edmonton, Alberta T6E 5V2
  • Paul Spevak SynPhar Laboratories Inc., #2, 4290-91А Street, Edmonton, Alberta T6E 5V2
  • Jadwiga Kaleta SynPhar Laboratories Inc., #2, 4290-91А Street, Edmonton, Alberta T6E 5V2
  • Ronald G. Micetich SynPhar Laboratories Inc., #2, 4290-91А Street, Edmonton, Alberta T6E 5V2
  • Samarendra N. Maiti SynPhar Laboratories Inc., #2, 4290-91А Street, Edmonton, Alberta T6E 5V2

Abstract

A new series of 2-spiro(2',2'-diphеnylcyclopropane) cephalosporin sulfones was synthesized as potent human leukocyte elastase inhibitors.

How to Cite
Narender Reddy, A. V.; Fiakpui, C. Y.; Czajkowski, D. P.; Spevak, P.; Kaleta, J.; Micetich, R. G.; Maiti, S. N. Chem. Heterocycl. Compd. 1998, 34, 1289. [Khim. Geterotsikl. Soedin. 1998, 34, 1517.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF02256809

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Published

1998-11-25

Issue

No. 11 (1998)

Section

Original Papers