Chemistry of Heterocyclic Compounds
type: channel
description: Chemistry of Heterocyclic Compounds (Khimiya Geterotsiklicheskikh Soedinenii) publishes articles, short communications, reviews and minireviews on the synthesis, structure, reactivity and biological activity of heterocyclic compounds including natural products. The journal covers investigations in heterocyclic chemistry taking place in scientific centers all over the world. CHEMISTRY OF HETEROCYCLIC COMPOUNDS is a translation of the journal Khimiya Geterotsiklicheskikh Soedinenii, which is issued by the Latvian Institute of organic synthesis. Editor-in-Chief: D. Volochnyuk Deputy Editors: P. Arsenyan, S. Ryabukhin Managing Editor: M. Teus Production Editors: N. Zhuk, A. Amoliņš Production Editor of the English Issue: N. Vereteņņikova Advisory Board: O. N. Chupakhin, G. Duburs, I. Kalvinsh, V. G. Kartsev, M. Makosza, V. I. Minkin, H. van der Plas, A. F. Pozharskii, A. A. Tolmachev, B. A. Trofimov, R. Valters, A. V. Varlamov Editorial Board: V. T. Abaev, A. V. Aksenov, N. A. Bumagin, V. A. Chebanov, S. M. Desenko, V. V. Dotsenko, L. L. Fershtat, V. Gevorgyan, B. Gnanaprakasam, O. O. Grygorenko, A. V. Gulevskaya, A. Gutnov, R. Jasiński, A. Kornienko, M. A. Kuznetsov, T. Opatz, V. A. Ostrovskii, A. E. Shchekotikhin, A. B. Sheremetev, Yu. G. Shermolovych, V. Z. Shirinian, V. Ya. Sosnovskikh, I. V. Trushkov, M. Turks, E. N. Ulomsky, A. V. Vasilyev, A. N. Vereshchagin, L. G. Voskressensky
publisher: Latvian Institute of Organic Synthesis
language: en-US
publication name: Chemistry of Heterocyclic Compounds
issn: 0132-6244
items: Cyanamides in heterodiene synthesis
items: Compounds of the thiophene series, accompanying aromatic hydrocarbons in technical mixtures: Complexes with organic solvents
items: Intramolecular cyclization of N-(4-aryl-5-pyrazolyl)formamidines
items: Reactions of polyhalopyridines. 9. Perfluoroalkylation of 2,3,5,6-tetrafluoro-4-mercaptopyridine with compounds of xenon containing fluorine
items: Arenesulfenylation of 1,3-azoles with arenesulfenyl chlorides
items: Molecular structure of 1-phenyl-2-chloro-3-(meta-nitrophenyl)-2,3-epoxypropanone
items: 2-benzopyrylium salts. 45. Interaction of 2-benzopyrylium salts and their monocyclic analogs with imines of ketones
items: Pyrylocyanines. 33. Pyrylocarbocyanines with bridge groups in the chromophore
items: Synthesis of some new derivatives of dithiene- and oxathienecarboxylic acids
items: Pyrroloindoles. 16. Some electrophilic substitution reactions of 2,7-dicarbethoxy-1H,6H-pyrrolo[2,3-e]indoles
items: Synthesis of novel benzoylated indoles
items: Synthesis of mono- and disubstituted tetra(tert-butyl)porphyrazines
items: Recyclization of spiro[3a-hydroxypiperidin-4,2′-oxiranes] in basic medium
items: Synthesis of spirocyclic 1,3-dioxolan-4-ones from α-hydroxyamides
items: Stereochemistry of hydrocyanation of 3-hydroxy-4-alkyliminopiperidines
items: Reactions of 4-ethoxycarbonylbenzo[c]pyrylium with ammonia and primary amines
items: Alkylation of 2-, 4-, and 8-trialkylsiloxyquinolines by methyl iodide
items: Quaternization of 1H-imidazo[4,5-b]pyridine and 4-methyl-4H-imidazo[4,5-b]pyridine
items: Amidoalkylation of mono- and dimercaptopyrimidines
items: Functionally substituted azines. 1. Synthesis and reactions of 2-(N-cyano-N-carbethoxmethylamino)-4,6-dimethylpyrimidine
items: Pyrrolopyrimidines. 1. Electrophilic substitution reactions of 1,3-dimethylpyrrolo[3,2-d]pyrimidine-2,4-dione
items: https://hgs.osi.lv/index.php/hgs/article/view/11185
items: Purines, pyrimidines, and condensed systems based on these compounds. 13. Transformation of fervenulin-1-oxide to 8-alkylaminotheophyllines under the action of alkylamines
items: Synthesis of 3-hydrazino-6-tert-butyl-1,2,4-triazolo[3,4-c]-1,2,4-triazin-5-one
items: Phosphorylnitrile oxides. 6. 1,3-cycloaddition with azomethines and nitriles
items: Phosphorylinitrile oxides. 7. Quantum chemical study of the dimerization of nitrile oxides
items: Rearrangement of 2-iminoperhydrothieno-[3,4-d]thiazole 5,5-dioxides
items: https://hgs.osi.lv/index.php/hgs/article/view/11179
items: https://hgs.osi.lv/index.php/hgs/article/view/11178

Cyanamides in heterodiene synthesis
type: item
description: The published data on the participation of cyanamides in heterodiene synthesis as dienophophiles were organized and generalized. How to Cite Nekrasov, D. D. Chem. Heterocycl. Compd. 1994, 30, 997. [Khim. Geterotsikl. Soedin. 1994, 1155.] For this article in the English edition, see DOI https://doi.org/10.1007/BF01171152
creator: Д. Д. Некрасов
rights: Copyright (c) 2026 Chemistry of Heterocyclic Compounds
date: 1994-09-25
publication date: 1994-09-25
number: 9
starting page: 1155
ending page: 1162

Compounds of the thiophene series, accompanying aromatic hydrocarbons in technical mixtures: Complexes with organic solvents
type: item
description: The data available in the literature on the complex formation of thiophene, its homologs, and benzannelated thiophenes with organic solvents have been reviewed. How to Cite Zaretskii, M. I. Chem. Heterocycl. Compd. 1994, 30, 1004. [Khim. Geterotsikl. Soedin. 1994, 1163.] For this article in the English edition, see DOI https://doi.org/10.1007/BF01171153
creator: M. И. Зарецкий
rights: Copyright (c) 2026 Chemistry of Heterocyclic Compounds
date: 1994-09-25
publication date: 1994-09-25
number: 9
starting page: 1163
ending page: 1171

Intramolecular cyclization of N-(4-aryl-5-pyrazolyl)formamidines
type: item
description: How to Cite Bogza, S. L.; Nikolyukin, Yu. A.; Dulenko, V. I. Chem. Heterocycl. Compd. 1994, 30, 1120. [Khim. Geterotsikl. Soedin. 1994, 1290.] For this article in the English edition, see DOI https://doi.org/10.1007/BF01171178
creator: C. Л. Богза
creator: Ю. А. Hиколюкин
creator: B. И. Дуленко
rights: Copyright (c) 2026 Chemistry of Heterocyclic Compounds
date: 1994-09-25
publication date: 1994-09-25
number: 9
starting page: 1290
ending page: 1290

Reactions of polyhalopyridines. 9. Perfluoroalkylation of 2,3,5,6-tetrafluoro-4-mercaptopyridine with compounds of xenon containing fluorine
type: item
description: How to Cite Sipyagin, A. M.; Efremov, I. V.; Pomytkin, I. A.; Kashtanov, S. A.; Aleinikov, N. N. Chem. Heterocycl. Compd. 1994, 30, 1121. [Khim. Geterotsikl. Soedin. 1994, 1291.] For this article in the English edition, see DOI https://doi.org/10.1007/BF01171179
creator: А. М. Сипягин
creator: И. В. Ефремов
creator: И. А. Помыткин
creator: C. А. Каштанов
creator: Н. Н. Алейников
rights: Copyright (c) 2026 Chemistry of Heterocyclic Compounds
date: 1994-09-25
publication date: 1994-09-25
number: 9
starting page: 1291
ending page: 1292

Arenesulfenylation of 1,3-azoles with arenesulfenyl chlorides
type: item
description: How to Cite Tolmachev, A. A.; Yurchenko, A. A.; Man'ko, V. A.; Merkulov, A. S.; Pinchuk, A. M. Chem. Heterocycl. Compd. 1994, 30, 1123. [Khim. Geterotsikl. Soedin. 1994, 1292.] For this article in the English edition, see DOI https://doi.org/10.1007/BF01171180
creator: А. А. Толмачев
creator: А. А. Юрченко
creator: В. А. Манько
creator: А. C. Меркулов
creator: А. M. Пинчyк
rights: Copyright (c) 2026 Chemistry of Heterocyclic Compounds
date: 1994-09-25
publication date: 1994-09-25
number: 9
starting page: 1292
ending page: 1293

Molecular structure of 1-phenyl-2-chloro-3-(meta-nitrophenyl)-2,3-epoxypropanone
type: item
description: X-ray analysis was used to determined the structure of 1-phenyl-2-chloro-3-(m-nitrophenyl)-2,3-epoxypropanone, obtained by reacting phenacyl dihydrochloride with metanitrobenzaldehyde under Darzen's reaction conditions. The bulky m-nitrophenyl and benzoyl substituents were located in the trans position relative to the chloroepoxide fragment, which was found to stabilize when the m-nitrophenyl substituent was introduced. How to Cite Litvinov, I. A.; Mamedov, V. A.; Kataeva, O. N. Chem. Heterocycl. Compd. 1994, 30, 1012. [Khim. Geterotsikl. Soedin. 1994, 1172.] For this article in the English edition, see DOI https://doi.org/10.1007/BF01171154
creator: И. А. Литвинов
creator: В. А. Мамедов
creator: O. H. Катаева
rights: Copyright (c) 2026 Chemistry of Heterocyclic Compounds
date: 1994-09-25
publication date: 1994-09-25
number: 9
starting page: 1172
ending page: 1175

2-benzopyrylium salts. 45. Interaction of 2-benzopyrylium salts and their monocyclic analogs with imines of ketones
type: item
description: It was shown that ketonimines, which can have imine--enamine tautomerism, react with pyrylium salts in the enamined form. In such reactions, the 2-benzopyrylium salts are transformed into unsaturated ketones, and their monocyclic analogs are transformed into either quinolizinium salts or pyridinium salts depending on the structure of the initial imine. How to Cite Tosunyan, D. É.; Verin, S. V.; Kuznetsov, E. V. Chem. Heterocycl. Compd. 1994, 30, 0151. [Khim. Geterotsikl. Soedin. 1994, 1176.] For this article in the English edition, see DOI https://doi.org/10.1007/BF01171155
creator: Д. Э. Тосунян
creator: C. В. Верин
creator: E. В. Кузнецов
rights: Copyright (c) 2026 Chemistry of Heterocyclic Compounds
date: 1994-09-25
publication date: 1994-09-25
number: 9
starting page: 1176
ending page: 1185

Pyrylocyanines. 33. Pyrylocarbocyanines with bridge groups in the chromophore
type: item
description: Salts of 4,4-tetra-, penta-, and hexamethylene-bis-(2,6-diphenylpyrylium) and -thiopyrylium were synthesized and used as the basis for producing trimethylcyanines with ethylene, tri- and tetramethylene bridge groups in the chromophore. Factors influencing the color of these dyes were analyzed. The bis-pyrylium salts were converted to derivatives of pyridine, N-methyl- and N-phenylpyridinium. The structure of the compounds obtained was confirmed by the data of electron spectroscopy and PMR spectroscopy. How to Cite Kudinova, M. A.; Maiboroda, E. I.; Slominskii, Yu. L.; Tolmachev, A. I. Chem. Heterocycl. Compd. 1994, 30, 1024. [Khim. Geterotsikl. Soedin. 1994, 1186.] For this article in the English edition, see DOI https://doi.org/10.1007/BF01171156
creator: M. А. Кудинова
creator: E. И. Майборода
creator: Ю. Л. Сломинский
creator: А. И. Толмачев
rights: Copyright (c) 2026 Chemistry of Heterocyclic Compounds
date: 1994-09-25
publication date: 1994-09-25
number: 9
starting page: 1186
ending page: 1190

Synthesis of some new derivatives of dithiene- and oxathienecarboxylic acids
type: item
description: Substituted anilides of 1,4-dithiene- and oxathienecarboxylic acids were synthesized. It was shown that the reaction of 3-phenyl-1,4-dithi-2-ene-2-carboxyl chloride with 2-aminopyridines, depending on the base used and the reaction conditions, leads to the formation of N-[3′-phenyl-2′-(1′,4′-dithi-2′-en)ylcarbonyl]2-aminopyridine and/or N,N′-bis[3-phenyl-2-(1,4-dithi-2-en)-ylcarbonyl]pyridonimine. The data of IR, UV, and PMR spectroscopy were used to confirm the structure of the synthesized compounds. How to Cite Mamedov, V. A.; Sibgatullina, F. G.; Gubskaya, V. P.; Gainullin, R. M.; Shagidullin, R. R.; Il'yasov, A. V. Chem. Heterocycl. Compd. 1994, 30, 1029. [Khim. Geterotsikl. Soedin. 1994, 1191.] For this article in the English edition, see DOI https://doi.org/10.1007/BF01171157
creator: В. А. Мамедов
creator: Ф. Г. Сибгатyллина
creator: B. П. Губская
creator: Р. М. Гайнуллин
creator: Р. P. Шагидуллин
creator: А. В. Ильясов
rights: Copyright (c) 2026 Chemistry of Heterocyclic Compounds
date: 1994-09-25
publication date: 1994-09-25
number: 9
starting page: 1191
ending page: 1196

Pyrroloindoles. 16. Some electrophilic substitution reactions of 2,7-dicarbethoxy-1H,6H-pyrrolo[2,3-e]indoles
type: item
description: Electrophilic substitutions of 2,7-dicarbethoy-1H,6H-pyrrolo[2,3-e]indole (Friedel‒Crafts acylation, nitration, bromination) take place both at position 3 of the indole ring and at positions 5 and 8 in the benzene ring. How to Cite Lomadze, N. S.; Chikvaidze, I. Sh.; Targamadze, N. L.; Kurkovskaya, L. N.; Samsoniya, Sh. A.; Suvorov, N. N. Chem. Heterocycl. Compd. 1994, 30, 1034. [Khim. Geterotsikl. Soedin. 1994, 1197.] For this article in the English edition, see DOI https://doi.org/10.1007/BF01171158
creator: H. Ш. Ломадзе
creator: И. Ш. Чикваидзе
creator: Н. Л. Таргамадзe
creator: Л. Н. Kypковскaя
creator: Ш. А. Cамcония
creator: H. H. Суворов
rights: Copyright (c) 2026 Chemistry of Heterocyclic Compounds
date: 1994-09-25
publication date: 1994-09-25
number: 9
starting page: 1197
ending page: 1201

Synthesis of novel benzoylated indoles
type: item
description: It has been shown that Friedel‒Crafts p-nitrobenzoylation of 2,2′-dicarbethoxybis(5-indoyl)methane occurs at the bridging group. From the products of p-nitrobenzoylation of 2-carbethoxy-5-methylindole, 2-carbethoxy-5-hydroxy-indole and 2,7-dicarbethoxy-1H,6H-pyrrolo[2,3-e]indole there were obtained corresponding amines and an oxime. How to Cite Samsoniya, Sh. A.; Chikvaidze, I. Sh.; Gogrichiani, É. O.; Lomadze, N. Sh.; Targamadze, N. L. Chem. Heterocycl. Compd. 1994, 30, 1039. [Khim. Geterotsikl. Soedin. 1994, 1202.] For this article in the English edition, see DOI https://doi.org/10.1007/BF01171159
creator: Ш. А. Самсония
creator: И. Ш. Чикваидзе
creator: Э. О. Гогричиани
creator: H. Ш. Ломадзе
creator: Н. Л. Tаргaмaдзе
rights: Copyright (c) 2026 Chemistry of Heterocyclic Compounds
date: 1994-09-25
publication date: 1994-09-25
number: 9
starting page: 1202
ending page: 1205

Synthesis of mono- and disubstituted tetra(tert-butyl)porphyrazines
type: item
description: Bromination of tetra(tert-butyl)porphyrazine by N-bromosuccinimide in chloroform results in the formation of mono- and dibromides, substitution for the bromine atoms of which produced the corresponding cyano, phenoxy, phenylthio, styryl, phenylethynyl and piperidino derivatives. From the monobromide and 2,2-bis(p-hydroxyphenyl)propane, the dimeric porphyrazine 2,2-bis[p-tetra(tert-butyl)porphyrazyloxyphenyl]propane was similarly obtained. How to Cite Makarova, E. A.; Kopranenkov, V. N.; Shevtsov, V. K.; Luk'yanets, E. A. Chem. Heterocycl. Compd. 1994, 30, 1043. [Khim. Geterotsikl. Soedin. 1994, 1206.] For this article in the English edition, see DOI https://doi.org/10.1007/BF01171160
creator: Е. А. Макарова
creator: В. Н. Копраненков
creator: В. К. Шевцов
creator: E. А. Лукьянец
rights: Copyright (c) 2026 Chemistry of Heterocyclic Compounds
date: 1994-09-25
publication date: 1994-09-25
number: 9
starting page: 1206
ending page: 1212

Recyclization of spiro[3a-hydroxypiperidin-4,2′-oxiranes] in basic medium
type: item
description: It is shown that heating spiro[3a-hydroxypiperidin-4,2′-oxiranes] in aqueous base gives rearrangement into derivatives of 3,4-epoxypiperidines. The structures of the latter were confirmed by spectral data and by chemical informations. How to Cite Zvonok, A. M.; Okaev, E. B. Chem. Heterocycl. Compd. 1994, 30, 1049. [Khim. Geterotsikl. Soedin. 1994, 1213.] For this article in the English edition, see DOI https://doi.org/10.1007/BF01171161
creator: А. М. Звонок
creator: Е. Б. Окаев
rights: Copyright (c) 2026 Chemistry of Heterocyclic Compounds
date: 1994-09-25
publication date: 1994-09-25
number: 9
starting page: 1213
ending page: 1215

Synthesis of spirocyclic 1,3-dioxolan-4-ones from α-hydroxyamides
type: item
description: It is shown that α,β-dihydroxypiperidine-4-carboxyamides in reaction with formaldehyde in concentrated sulfuric acid is converted to the corresponding 1,3-dioxolan-4-ones. How to Cite Lakhvich, F. F.; Stanishevskii, L. S. Chem. Heterocycl. Compd. 1994, 30, 1052. [Khim. Geterotsikl. Soedin. 1994, 1216.] For this article in the English edition, see DOI https://doi.org/10.1007/BF01171162
creator: Ф. Ф. Лахвич
creator: Л. С. Станишевский
rights: Copyright (c) 2026 Chemistry of Heterocyclic Compounds
date: 1994-09-25
publication date: 1994-09-25
number: 9
starting page: 1216
ending page: 1218

Stereochemistry of hydrocyanation of 3-hydroxy-4-alkyliminopiperidines
type: item
description: We have studied the stereochemistry of hydrocyannation of 3-hydroxy-4-alkyliminopiperidines. We have developed preparative synthesis methods for stereoisomeric 4-alkylamino-3e-hydroxy-1,3a-dimethyl-6e-(4-chlorophenyl)piperidines. How to Cite Lakhvich, F. F.; Khripach, N. B.; Stanishevskii, L. S. Chem. Heterocycl. Compd. 1994, 30, 1055. [Khim. Geterotsikl. Soedin. 1994, 1219.] For this article in the English edition, see DOI https://doi.org/10.1007/BF01171163
creator: Ф Ф. Лахвич
creator: Н. Б. Хрипач
creator: Л. С. Станишевский
rights: Copyright (c) 2026 Chemistry of Heterocyclic Compounds
date: 1994-09-25
publication date: 1994-09-25
number: 9
starting page: 1219
ending page: 1221

Reactions of 4-ethoxycarbonylbenzo[c]pyrylium with ammonia and primary amines
type: item
description: We have studied the reactions of 4-ethoxycarbonylbenzo[c]pyrylium perchlorates with ammonia and primary amines. We have obtained previously unknown derivatives of isoquinoline and 1-naphthylamine. How to Cite Bogza, S. L.; Zubritskii, M. Yu.; Dulenko, V. I. Chem. Heterocycl. Compd. 1994, 30, 1058. [Khim. Geterotsikl. Soedin. 1994, 1222.] For this article in the English edition, see DOI https://doi.org/10.1007/BF01171164
creator: C. Л. Богза
creator: M. Ю. Зубрицкий
creator: В. И. Дуленко
rights: Copyright (c) 2026 Chemistry of Heterocyclic Compounds
date: 1994-09-25
publication date: 1994-09-25
number: 9
starting page: 1222
ending page: 1224

Alkylation of 2-, 4-, and 8-trialkylsiloxyquinolines by methyl iodide
type: item
description: Trimethyl- and triethylsilyl ethers of 2-, 4-, and 8-hydroxyquinolines have been prepared. The alkylation of these siloxyquinolines by methyl iodide has been studied. In the case of 4-trimethylsiloxyquinoldine, it has been established that both N- and O-alkylation products are formed. How to Cite Lukevits, É.; Segal, I.; Birgele, I.; Zablotskaya, A. Chem. Heterocycl. Compd. 1994, 30, 1061. [Khim. Geterotsikl. Soedin. 1994, 1225.] For this article in the English edition, see DOI https://doi.org/10.1007/BF01171165
creator: Э. Лукeвиц
creator: И. Сегал
creator: И. Биргеле
creator: А. Заблоцкая
rights: Copyright (c) 2026 Chemistry of Heterocyclic Compounds
date: 1994-09-25
publication date: 1994-09-25
number: 9
starting page: 1225
ending page: 1231

Quaternization of 1H-imidazo[4,5-b]pyridine and 4-methyl-4H-imidazo[4,5-b]pyridine
type: item
description: Unsubstituted imidazo[4,5-b]pyridine adds methyl iodide to the pyridine N atom. Treatment of the resulting iodide with base forms 4-methyl-4H-imidazo[4,5-b]pyridine. This nucleophile can readily add methyl iodide to form only one salt, 1,4-dimethylimidazo[4,5-b]pyridinium iodide. How to Cite Yutilov, Yu. M.; Ignatenko, A. G. Chem. Heterocycl. Compd. 1994, 30, 1067. [Khim. Geterotsikl. Soedin. 1994, 1232.] For this article in the English edition, see DOI https://doi.org/10.1007/BF01171166
creator: Ю. М. Ютилов
creator: А. Г. Игнатенко
rights: Copyright (c) 2026 Chemistry of Heterocyclic Compounds
date: 1994-09-25
publication date: 1994-09-25
number: 9
starting page: 1232
ending page: 1233

Amidoalkylation of mono- and dimercaptopyrimidines
type: item
description: Reaction of 2- and 4-mercapto- and 2,4-dimercaptopyrimidines with N-(1-chloroalkyl)amides of carboxylic acids and N-acylimines forms only the S-substituted products. How to Cite Klyuchko, S. V.; Khutova, B. M.; Prikazchikova, L. P. Chem. Heterocycl. Compd. 1994, 30, 1069. [Khim. Geterotsikl. Soedin. 1994, 1234.] For this article in the English edition, see DOI https://doi.org/10.1007/BF01171167
creator: С. B. Ключко
creator: Б. М. Хутова
creator: Л. П. Приказчикова
rights: Copyright (c) 2026 Chemistry of Heterocyclic Compounds
date: 1994-09-25
publication date: 1994-09-25
number: 9
starting page: 1234
ending page: 1238

Functionally substituted azines. 1. Synthesis and reactions of 2-(N-cyano-N-carbethoxmethylamino)-4,6-dimethylpyrimidine
type: item
description: Treatment of 2-(N-potassium-N-cyanamino)-4,6-dimethylpyrimidine with ethyliodoacetate produces 2-(N-cyano-N-carbethoxymethylamino)-4,6-dimethylpyrimidine. Alkaline hydrolysis of the last gives 2-(3-potassium-2,4-dioxoimidazolidinyl-1)-4,6-dimethylpyrimidine. Ammonolysis and hydrazinolysis give imino- or amino-imidazolidinylpyrimidine, respectively. How to Cite Dovlatyan, V. V.; Éliazyan, K. A.; Pivazyan, V. A. Chem. Heterocycl. Compd. 1994, 30, 1074. [Khim. Geterotsikl. Soedin. 1994, 1239.] For this article in the English edition, see DOI https://doi.org/10.1007/BF01171168
creator: В. В. Довлатян
creator: К. А. Элиaзян
creator: В. А. Пивазян
rights: Copyright (c) 2026 Chemistry of Heterocyclic Compounds
date: 1994-09-25
publication date: 1994-09-25
number: 9
starting page: 1239
ending page: 1241

Pyrrolopyrimidines. 1. Electrophilic substitution reactions of 1,3-dimethylpyrrolo[3,2-d]pyrimidine-2,4-dione
type: item
description: The reactions of halogenation, aminomethylation, acylation, and azo coupling in 1,3-dimethylpyrrolo[3,2-d]pyrimidine-2,4 dione proceed at position 7, whereas nitration in acetic acid is directed primarily to position 6. In a some of cases, products of substitution of both hydrogen atoms in the pyrrole ring have been synthesized. How to Cite Tsupak, E. B.; Tkachenko, Yu. N.; Pozharskii, A. F. Chem. Heterocycl. Compd. 1994, 30, 1077. [Khim. Geterotsikl. Soedin. 1994, 1242.] For this article in the English edition, see DOI https://doi.org/10.1007/BF01171169
creator: Е. Б. Цупак
creator: Ю. H. Ткаченко
creator: А. Ф. Пожарский
rights: Copyright (c) 2026 Chemistry of Heterocyclic Compounds
date: 2026-05-14
publication date: 2026-05-14
number: 9
starting page: 1242
ending page: 1248

https://hgs.osi.lv/index.php/hgs/article/view/11185
type: item
title: Purines, pyrimidines, and condensed systems based on these compounds. 12. 1,3-Dimethylpyrimido[4,5-d]pyrimidine-2,4-(1H,3H)dione: The first case of regioselective amination of condensed pyrimidines in position 2
description: 1,3-Dimethylpyrimido[4,5-d]pyrimidine-2,4-(1H,3H)dione (l) reacts with alkylamides in liquid ammonia in the presence of an oxidizing agent such as KMnO4 or Ag(C5H5N)2MnO4, giving 7-amino derivatives; but the interaction of (1) with methylamine gives a mixture of isomeric alkylaminated products. Subsequent hydrolysis of the 7-piperidino derivatives in an alkaline medium and then in an article medium gives 4-methylamino-2-piperidinopyrimidine with quantitative yield. How to Cite Gulevskaya, A. V.; Pozharskii, A. F.; Shorshnev, S. V.; Zheltushkina, E. A. Chem. Heterocycl. Compd. 1994, 30, 1083. [Khim. Geterotsikl. Soedin. 1994, 1249.] For this article in the English edition, see DOI https://doi.org/10.1007/BF01171170
creator: А. B. Гулeвскaя
creator: А. Ф. Пожарский
creator: C. B. Шоpшнев
creator: Е. А. Желтушкина
rights: Copyright (c) 2026 Chemistry of Heterocyclic Compounds
date: 1994-09-25
publication date: 1994-09-25
number: 9
starting page: 1249
ending page: 1252

Purines, pyrimidines, and condensed systems based on these compounds. 13. Transformation of fervenulin-1-oxide to 8-alkylaminotheophyllines under the action of alkylamines
type: item
description: Fervenulin-1-oxide undergoes reactions with secondary alkylamines in which the triazine ring is ruptured and 8-alkylaminotheophyllines are formed. The final product of the interaction of fervenulin-1-oxide with primary amines or with liquid ammonia is 1,3-dimethyl-5-imino-6-hydroximinouracil. How to Cite Gulevskaya, A. V.; Pozharskii, A. F.; Shvidchenko, S. V. Chem. Heterocycl. Compd. 1994, 30, 1087. [Khim. Geterotsikl. Soedin. 1994, 1253.] For this article in the English edition, see DOI https://doi.org/10.1007/BF01171171
creator: A. B. Гулевская
creator: А. Ф. Пожарский
creator: C. B. Швидченко
rights: Copyright (c) 2026 Chemistry of Heterocyclic Compounds
date: 1994-09-25
publication date: 1994-09-25
number: 9
starting page: 1253
ending page: 1257

Synthesis of 3-hydrazino-6-tert-butyl-1,2,4-triazolo[3,4-c]-1,2,4-triazin-5-one
type: item
description: 3-Hydrazino-6-tert-butyl-1,2,4-triazolo[3,4-c]-1,2,4-triazin-5-one was synthesized by the reaction of a substituted 4-(N,N-dimethylcarbamoyl)-3-thioxo-1,2,4-triazine with hydrazine. The spectral characteristics and the proposed reaction mechanism are discussed. How to Cite Mironovich, L. M. Chem. Heterocycl. Compd. 1994, 30, 1092. [Khim. Geterotsikl. Soedin. 1994, 1258.] For this article in the English edition, see DOI https://doi.org/10.1007/BF01171172
creator: Л. М. Миронович
rights: Copyright (c) 2026 Chemistry of Heterocyclic Compounds
date: 1994-09-25
publication date: 1994-09-25
number: 9
starting page: 1258
ending page: 1260

Phosphorylnitrile oxides. 6. 1,3-cycloaddition with azomethines and nitriles
type: item
description: The 1,3-dipolar cycloaddition of diisopropoxyphosphorylnitrile oxide to Schiff bases gives 3-diisopropoxyphosphoryl-4-R-5-phenyl-1,2,4-oxadiazolines. The cycloaddition of phosphorylated nitrile oxides at the azomethine bond of hydrazones does not proceed due to the low dipolarophilic activity of the CH = N bond and high tendency of phosphorylnitrile oxidesto undergo dimerization and polymerization. The reaction of nitrile oxides with 2-hydroxybenzylidenaniline leads to the corresponding ester of diisopropoxyphosphorylformhydroxamic acid. The nitrile group undergoes cycloaddition only when activated. The reaction of a solution of phosphorylnitrile oxides in benzene with tetracyanoethylene gives the bisadduct at the two C = N bonds without affecting the C = C bond. How to Cite Pavlov, V. A.; Kurdyukov, A. I.; Moskva, V. V. Chem. Heterocycl. Compd. 1994, 30, 1095. [Khim. Geterotsikl. Soedin. 1994, 1261.] For this article in the English edition, see DOI https://doi.org/10.1007/BF01171173
creator: B. А. Павлов
creator: А. И. Курдюков
creator: В. В. Москва
rights: Copyright (c) 2026 Chemistry of Heterocyclic Compounds
date: 1994-09-25
publication date: 1994-09-25
number: 9
starting page: 1261
ending page: 1268

Phosphorylinitrile oxides. 7. Quantum chemical study of the dimerization of nitrile oxides
type: item
description: A semiempirical MNDO calculation was carried out for the singlet potential energy surface for the dimerization of acetonitrile oxide leading to dimethylfuroxane. The dimerization of nitrile oxides proceeds by a two-step mechanism. The rate-limiting step is formation of a dinitrosoethylene intermediate. A semiempirical AMI calculation was carried out to study the effect of phosphoryl substituents on formation of the transition state of the rate-limiting step in the dimerization of dimethoxyphosphorylnitrile oxide. Independently of the initial orientation of the two phosphorylnitrile oxide molecules, a gauche-oriented dimeric species is formed in the first step in the dimerization. There is hardly any specific effect ofthe phosphoryl substituents in the first step of phosphorylnitrile oxide dimerization. How to Cite Kurdyukov, A. I.; Pavlov, V. A.; Gorin, B. I. Chem. Heterocycl. Compd. 1994, 30, 1101. [Khim. Geterotsikl. Soedin. 1994, 1269.] For this article in the English edition, see DOI https://doi.org/10.1007/BF01171174
creator: А. И. Курдюков
creator: В. А. Павлов
creator: Б. И. Горин
rights: Copyright (c) 2026 Chemistry of Heterocyclic Compounds
date: 1994-09-25
publication date: 1994-09-25
number: 9
starting page: 1269
ending page: 1273

Rearrangement of 2-iminoperhydrothieno-[3,4-d]thiazole 5,5-dioxides
type: item
description: The reaction of 4-bromo-2-thiolene 1,1-dioxide with thiosemicarbazide and thiosemicarbazones gave 2-iminoperhydrothieno[3,4-d]thiazole 5,5-dioxides, which contain a nitrogen function at the imino group. The recyclization of these compounds was studied. How to Cite Makarenko, A. G.; Parkhomenko, P. I.; Rozhenko, A. B.; Grigor'ev, A. A.; Rybakova, M. V.; Bezuglyi, Yu. V. Chem. Heterocycl. Compd. 1994, 30, 1106. [Khim. Geterotsikl. Soedin. 1994, 1274.] For this article in the English edition, see DOI https://doi.org/10.1007/BF01171175
creator: А. Г. Макаренко
creator: П. И. Пархоменко
creator: А. Б. Роженко
creator: А. А. Григорьев
creator: М. В. Рыбакова
creator: Ю. В. Безуглый
rights: Copyright (c) 2026 Chemistry of Heterocyclic Compounds
date: 1994-09-25
publication date: 1994-09-25
number: 9
starting page: 1274
ending page: 1277

https://hgs.osi.lv/index.php/hgs/article/view/11179
type: item
title: Reactions of polyhalopyridines. 8. Reactions of polychlorotrifluoromethyl-pyridines with sodium N,N-dimethyldithiocarbamate. Structure of the 8-trifluoromethylbis-1,3-dithiolo-[4,5-b:4′,5′-e]-pyridine-2,6-dione molecule
description: The reaction of the isomeric tetrachloro-α-, β-, and γ-trifluoromethylpyridines and of 3,4,5-trichloro-2-trifluoromethylpyridine with sodium N,N-dimethyldithiocarbamate dihydrate has been studied. In the case of the α-, and γ-isomers an intramolecular cyclization with the formation of 1,3-dithiol-2-one derivatives occurs and the remaining compounds give only products of mono- or disubstitution of chlorine atoms by a dithiocarbamate fragment at positions 4 or 6 of the pyridine ring. The structure of the compounds synthesized was proved using 13C NMR and X-ray crystallographic analysis. How to Cite Sipyagin, A. M.; Aliev, Z. G. Chem. Heterocycl. Compd. 1994, 30, 1278. [Khim. Geterotsikl. Soedin. 1994, 1.] For this article in the English edition, see DOI https://doi.org/10.1007/BF01171176
creator: А. М. Сипягин
creator: З. Г. Алиев
rights: Copyright (c) 2026 Chemistry of Heterocyclic Compounds
date: 1994-09-25
publication date: 1994-09-25
number: 9
starting page: 1278
ending page: 1284

https://hgs.osi.lv/index.php/hgs/article/view/11178
type: item
title: Pyrimidotetrathiafulvalenes. 2. Trimethylsilylation of 5,-dioxo(4H,6H)-1,3-dithiolo[4,5-d]pyrimidine-2-selone and the use of the silylated product for the synthesis of 2,4-dioxopyrimidotetrathiafulvalenes
description: The trimethylsilylation of 5,7-dioxo(4H,6H)-1,3-dithiolo[4,5-d]pyrimidine-2-selone with bis(trimethylsilyl)acetamide enables pyrimido-tetrathiafulvalene derivatives to be prepared in benzene solution and increases the yield of the target compounds compared with the reaction of the unsilylated selone in DMF solution. The intermediate 2,4-bis(trimethylsilyloxy)pyrimidotetrathiafulvalenes were sensitive to hydrolysis. The previously undescribed [2,4-dioxo(1H,3H)pyrimido]di(methylthio)tetrathifulvalene has been obtained. The redox properties of the compounds obtained have been investigated by cyclic current-potential measurements. How to Cite Neiland, O. Ya.; Tilika, V. Z.; Edzhinya, A. S. Chem. Heterocycl. Compd. 1994, 30, 1116. [Khim. Geterotsikl. Soedin. 1994, 1285.] For this article in the English edition, see DOI https://doi.org/10.1007/BF01171177
creator: O. Я. Нейланд
creator: В. Ж. Тилика
creator: А. C. Эджиня
rights: Copyright (c) 2026 Chemistry of Heterocyclic Compounds
date: 1994-09-25
publication date: 1994-09-25
number: 9
starting page: 1285
ending page: 1289