ONE-STEP FACILE SYNTHESIS OF L-PROLINE ETHYLAMIDE HYDROCHLORIDE

Abstract

One-step facile synthesis of a L-proline ethylamide  hydrochloride  
from L-proline in good yields via the cyclic silicon intermediate
is described. This is the first example of the efficient synthesis
of a alkylamide proline performed without protect-unprotect methods
and suitable for large scale preparation.

How to Cite
Balaev, A. N.; Okmanovich, K. A.; Osipov, V. N.; Fedorov, V. E. Chem. Heterocycl. Compd. 2014, 50, 287. [Khim. Geterotsikl. Soedin. 2014, 315.]

For this article in the English edition see DOI 10.1007/s10593-014-1474-7