AN EFFICIENT ONE-POT THREE-COMPONENT SYNTHESIS OF PYRIMIDO[4,5-<i>d</i>]PYRIMIDINE DERIVATIVES IN AQUEOUS MEDIUM

Authors

  • Sreedhar Badvel Department of Chemistry, Vikrama Simhapuri University, Nellore-524 003, Andhra Pradesh
  • Raveendra Reddy Gopireddy Department of Chemistry, Vikrama Simhapuri University, Nellore-524 003, Andhra Pradesh
  • Thaslim Basha Shaik Department of Chemistry, Sri Venkateswara University, Tirupati-517 502, Andhra Pradesh
  • Sudhamani Hasti Department of Chemistry, Sri Venkateswara University, Tirupati-517 502, Andhra Pradesh
  • Veera Reddy Tummaluru Department of Chemistry, Vikrama Simhapuri University, Nellore-524 003, Andhra Pradesh
  • Naga Raju Chamarthi Department of Chemistry, Vikrama Simhapuri University, Nellore-524 003, Andhra Pradesh

DOI:

https://doi.org/10.1007/2266

Keywords:

6-amino-N, N-dimethyluracil, phenylisocyanate, phenylisothiocyanate, Lewis acid, PEG-bound sulfonic acid, threecomponent reaction

Abstract

A fast, efficient, and green synthesis of pyrimido[4,5-d]pyrimidine derivatives has been achieved via one-pot three-component reaction starting from 6-amino-N,N-dimethyluracil, phenylisothiocyanate or phenylisocyanate, and aromatic aldehydes in the presence of polyethylene glycol-bound sulfonic acid as a catalyst in water as solvent.

How to Cite
Badvel, S.; Gopireddy, R. R.; Basha Shaik, T.; Hasti, S.; Tummaluru, V. R.; Chamarthi, N. R. Chem. Heterocycl. Compd. 2015, 51, 749. [Khim. Geterotsikl. Soedin. 2015, 51, 749.]

For this article in the English edition see DOI 10.1007/s10593-015-1769-3

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Published

2015-08-28

Issue

Vol. 51 No. 8 (2015)

Section

Original Papers