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AN EFFICIENT ONE-POT THREE-COMPONENT SYNTHESIS OF PYRIMIDO[4,5-d]PYRIMIDINE DERIVATIVES IN AQUEOUS MEDIUM

Sreedhar Badvel, Raveendra Reddy Gopireddy, Thaslim Basha Shaik, Sudhamani Hasti, Veera Reddy Tummaluru, Naga Raju Chamarthi
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Abstract


A fast, efficient, and green synthesis of pyrimido[4,5-d]pyrimidine derivatives has been achieved via one-pot three-component reaction starting from 6-amino-N,N-dimethyluracil, phenylisothiocyanate or phenylisocyanate, and aromatic aldehydes in the presence of polyethylene glycol-bound sulfonic acid as a catalyst in water as solvent.

How to Cite
Badvel, S.; Gopireddy, R. R.; Basha Shaik, T.; Hasti, S.; Tummaluru, V. R.; Chamarthi, N. R. Chem. Heterocycl. Compd. 2015, 51, 749. [Khim. Geterotsikl. Soedin. 2015, 51, 749.]

For this article in the English edition see DOI 10.1007/s10593-015-1769-3


Keywords


6-amino-N,N-dimethyluracil; phenylisocyanate; phenylisothiocyanate; Lewis acid; PEG-bound sulfonic acid; threecomponent reaction

Full Text: PDF Supplementary File(s): Supporting information (6MB)


 

 

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