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SYNTHESIS OF 2-AMINO-4H-1,3-OXAZINES AND 2-AMINO-4H-1,3-THIAZINES THROUGH A Yb(OTf)3-ASSISTED, ACID-CATALYZED ONE-POT CYCLOCONDENSATION REACTION

Salil Putatunda, Arijit Chakraborty
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Abstract


An efficient synthesis of 2-amino-4,6-diaryl-4H-1,3-oxazine and 2-amino-4,6-diaryl-4H-1,3-thiazine derivatives has been demonstrated through a one-pot multicomponent cyclocondensation reaction. Ytterbium triflate and concentrated HCl has been utilized as the catalyst system for this reaction. The method produced good to excellent product yields and allowed a wide variation of the substituents in both aryl moieties.

How to Cite
Putatunda, S.; Chakraborty, A. Chem. Heterocycl. Compd. 2015, 51, 763. [Khim. Geterotsikl. Soedin. 2015, 51, 763.]

For this article in the English edition see DOI 10.1007/s10593-015-1770-x


Keywords


2-amino-4H-1,3-oxazine; 2-amino-4H-1,3-thiazine; ytterbium triflate; hetero Diels–Alder reaction; multicomponent reaction

Full Text: PDF Supplementary File(s): Supporting information (6MB)


 

 

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