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SYNTHESIS OF NEW 2-[2-(DIALKYL(DIARYL)PHOSPHORYL)-2-METHYLPROPYL]QUINOLINE-4-CARBOXYLIC ACIDS

Дмитрий А. Татаринов, Виктория И. Осипова, Андрей В. Богданов, Дмитрий Б. Криволапов, Александра Д. Волошина, Владимир Ф. Миронов
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Abstract


A Pfitzinger reaction of isatin with 2-methyl-(4-oxopent-2-yl)dialkyl(diphenyl)phosphine oxides was used to synthesize new derivatives of 4-quinolinecarboxylic acids, containing a phosphine oxide fragment, and screening for antimicrobial activity was performed.

How to Cite
Tatarinov, D. A.; Osipova, V. I.; Bogdanov, A. V.; Krivolapov, D. B.; Voloshina, A. D.; Mironov, V. F. Chem. Heterocycl. Compd. 2015, 51, 717. [Khim. Geterotsikl. Soedin. 2015, 51, 717.]

For this article in the English edition see DOI 10.1007/s10593-015-1761-y


Keywords


dimephosphone; isatin; 4-phosphoryl ketones; quinoline; quinolinecarboxylic acids; Pfitzinger reaction

Full Text: PDF (Russian) Supplementary File(s): SUPPLEMENTARY INFORMATION (614KB)


 

 

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