FEATURES OF THE AMINOMETHYLATION OF 7-HYDROXY-4'-FLUOROISOFLAVONES WITH PRIMARY AMINES

Authors

  • С. П. Бондаренко Taras Shevchenko Kiev National University
  • М. С. Фрасинюк Taras Shevchenko Kiev National University
  • В. П. Хиля Taras Shevchenko Kiev National University

DOI:

https://doi.org/10.1007/2797

Keywords:

8-aminomethylisoflavones, 3-(4-fluorophenyl)-9, 10-dihydro-4H, 8H-chromeno[8, 7-e][1, 3]oxazin-4-ones, aminomethylation, electrophilic substitution

Abstract

The behavior of 7-hydroxy-4'-fluoroisoflavones under the conditions of the Mannich reaction with primary amines was studied. New 9-alkyl-substituted 3-(4-fluorophenyl)-9,10-dihydro-4H,8H-chromeno[8,7‑e][1,3]oxazin-4-ones were synthesized. A method was developed for the synthesis of 8-aminomethyl derivatives of isoflavones.

How to Cite
Bondarenko, S. P.; Frasinyuk, M. S.; Khilya, V. P. Chem. Heterocycl. Compd. 2010, 46, 146. [Khim. Geterotsikl. Soedin. 2010, 180.]

For this article in the English edition see DOI 10.1007/s10593-010-0485-2

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Published

2015-11-26

Issue

No. 2 (2010)

Section

Original Papers