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SYNTHESIS OF 1,2,4-TRIAZOLO[1,5-a]PYRIMIDINE SYSTEM

Maksym M. Fizer, Mikhailo V. Slivka
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Abstract


In this review article we have focused on synthetic approaches for the creation of [1,2,4]triazolo[1,5-a]pyrimidine system. The synthetic ways for the preparation of [1,2,4]triazolo[1,5-a]pyrimidines can be divided into two main groups: annulation of pyrimidine moiety to triazole ring and annulation of triazole fragment to pyrimidine ring. The Dimroth rearrangement of [1,2,4]triazolo[4,3-a]pyrimidines can also be used for the synthesis of [1,2,4]triazolo[1,5-a]pyrimidines.

How to Cite
Fizer, M.; Slivka, M. Chem. Heterocycl. Compd. 2016, 52, 155. [Khim. Geterotsikl. Soedin. 2016, 52, 155.]

For this article in the English edition see DOI 10.1007/s10593-016-1851-5


Keywords


essramycin; [1,2,4]triazolo[1,5-a]pyrimidines; Biginelli reaction

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