SYNTHESIS OF 1,2,4-TRIAZOLO[1,5-<i>a</i>]PYRIMIDINE SYSTEM

Authors

  • Maksym M. Fizer Faculty of Chemistry, Uzhhorod National University, 46 Pidhirna St., Uzhhorod 88000
  • Mikhailo V. Slivka Faculty of Chemistry, Uzhhorod National University, 46 Pidhirna St., Uzhhorod 88000

DOI:

https://doi.org/10.1007/2876

Keywords:

essramycin, [1, 2, 4]triazolo[1, 5-a]pyrimidines, Biginelli reaction

Abstract

In this review article we have focused on synthetic approaches for the creation of [1,2,4]triazolo[1,5-a]pyrimidine system. The synthetic ways for the preparation of [1,2,4]triazolo[1,5-a]pyrimidines can be divided into two main groups: annulation of pyrimidine moiety to triazole ring and annulation of triazole fragment to pyrimidine ring. The Dimroth rearrangement of [1,2,4]triazolo[4,3-a]pyrimidines can also be used for the synthesis of [1,2,4]triazolo[1,5-a]pyrimidines.

How to Cite
Fizer, M.; Slivka, M. Chem. Heterocycl. Compd. 2016, 52, 155. [Khim. Geterotsikl. Soedin. 2016, 52, 155.]

For this article in the English edition see DOI 10.1007/s10593-016-1851-5

Author Biographies

Maksym M. Fizer, Faculty of Chemistry, Uzhhorod National University, 46 Pidhirna St., Uzhhorod 88000

Maksym Mikhailovich Fizer

Lector, Organic Chemistry Department, Chemical Faculty

Mikhailo V. Slivka, Faculty of Chemistry, Uzhhorod National University, 46 Pidhirna St., Uzhhorod 88000

Mikhailo Vasiliovich Slivka

Associative Professor, Ph.D., Organic Chemistry Department, Chemical Faculty

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Published

2016-04-11

Issue

Vol. 52 No. 3 (2016)

Section

Heterocycles in Focus