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REACTIONS OF 2-(TRIFLUOROACETYL)CHROMONES WITH AROMATIC AMINES

Александр B. Сафрыгин, Дарья A. Ветюгова, Роман A. Иргашев, Вячеслав Я. Сосновских
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Abstract


Aromatic amines reacted with 2-(trifluoroacetyl)chromones as С- or N-nucleophiles, depending on the conditions. When the reaction was performed under solvent-free conditions at 100°С for 12–18 h, they acted as С-nucleophiles and gave bishetarylcarbinols in 21–67% yields, while in refluxing toluene the addition of primary arylamines occurred via the amino group, providing the corresponding hemiaminals (80–86%).

Authors: Alexander V. Safrygin, Darya A. Vetyugova, Roman A. Irgashev, Vyacheslav Ya. Sosnovskikh*


Keywords


anilines; bishetarylcarbinols; hemiaminals; 2-(trifluoroacetyl)chromones

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