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SYNTHESIS AND ANTIMYCOBACTERIAL ACTIVITY OF PYRIDINIUM COMPOUNDS WITH SULFONYLACETAMIDE SUBSTITUENT IN N-ALKYL CHAIN

Марина М. Шулаева, Марионелла А. Кравченко, Вячеслав Э. Семенов
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Abstract


Pyridines containing amine, amide, or hydrazide substituent were quaternized with (ω-haloalkyl)sulfonylacetamides, resulting in new pyridinium compounds that exhibited tuberculostatic activity against the strain H37Rv of Mycobacterium tuberculosis.

Authors: Marina M. Shulaeva*, Marionella A. Kravchenko, Vyacheslav E. Semenov


Keywords


carbamoylmethylsulfonyl group; pyridinium compounds; sulfonylacetamides; quaternization; antituberculosis activity

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