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CATALYST-FREE THREE-COMPONENT SYNTHESIS OF 2-AMINO-4,6-DIARYLPYRIDINE-3-CARBONITRILES UNDER SOLVENT-FREE CONDITIONS

Mohammad Hosein Sayahi, Seyyed Jafar Saghanezhad, Mohammad Mahdavi
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Abstract


A novel efficient one-pot synthesis of 2-amino-4,6-diarylpyridine-3-carbonitriles is described. Method involves heating the mixture of an acetophenone oxime, aldehyde, and malononitrile without any catalyst under solvent-free conditions to give the title compounds in good to high yields.

Keywords


acetophenone oximes; 2-amino-4,6-diarylpyridine-3-carbonitriles; solvent-free synthesis.

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