CATALYST-FREE THREE-COMPONENT SYNTHESIS OF 2-AMINO-4,6-DIARYLPYRIDINE-3-CARBONITRILES UNDER SOLVENT-FREE CONDITIONS

Авторы

  • Mohammad Hosein Sayahi Department of Chemistry, Payame Noor University, P. O. Box 19395-3697, Tehran, Iran
  • Seyyed Jafar Saghanezhad ACECR-Production Technology Research Institute, P. O. Box 61396-84689, Ahvaz, Iran
  • Mohammad Mahdavi Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, P. O. Box 14117-13137, Tehran, Iran

DOI:

https://doi.org/10.1007/4613

Ключевые слова:

acetophenone oximes, 2-amino-4, 6-diarylpyridine-3-carbonitriles, solvent-free synthesis.

Аннотация

A novel efficient one-pot synthesis of 2-amino-4,6-diarylpyridine-3-carbonitriles is described. Method involves heating the mixture of an acetophenone oxime, aldehyde, and malononitrile without any catalyst under solvent-free conditions to give the title compounds in good to high yields.

Загрузки

Опубликован

2019-08-15

Выпуск

Том 55 № 8 (2019)

Раздел

Оригинальные статьи