SYNTHESIS OF 2-[2-(HYDROXYIMINO)ALKYL]-1,2-OXAZOL-5(2Н)-ONES

Abstract

The reaction of α-hydroxyamino oximes with ethyl acetoacetate and ethyl α-methylacetoacetate yields 2-[2-(hydroxyimino)alkyl]-1,2-oxazol-5(2H)-ones. In the reaction of alkylaromatic α-hydroxyamino oximes with ethyl acetoacetate, the intermediate imidazo[1,2-b][1,2]oxazolones were isolated, which then convert to the target compounds.

Authors: Elena B. Nikolaenkova, Irina Yu. Bagryanskaya, Alexsei Ya. Tikhonov*